Protein Alignment PH4alphaNE1 and p4ha2

DIOPT Version :9

• Sequence 1: NP_733374.1
• Gene: PH4alphaNE1 / 43625
• FlyBaseID: FBgn0039780
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: XP_005173949.1
• Gene: p4ha2 / 373132
• ZFINID: ZDB-GENE-030827-1
• Length: 542
• Species: Danio rerio
• Alignment Length: 550
• Identity: 204/550 - (37%)
• Similarity: 316/550 - (57%)
• Gaps: 56/550 - (10%)

  Fly    10 LIFLLAQGSLAS----DYFSSITGLEDLLHTEQYLTRELRSKVNAIQTALQQLESELSSIEKEHT 70
            |:|||:..|.:|    :.|:||..:.:|:.||:.|.:.|:..:.|.:..|:.:.|..:.::|...
Zfish     5 LVFLLSTLSFSSPTRAEIFTSIGQMTNLIFTERELVQSLKEYIQAEEQKLETVRSWANKLDKLTR 69

  Fly    71 MAASDTENYLTNPVNVYRLMKRLHTDWSLMEGRVQLMAEE---MNFNATREYGLSYPSQEDVEGA 132
            .:.||.|.:|.:|||.|:|||||:|:||.:|..|.....:   .|.:..|:|   :|.:||.:||
Zfish    70 TSTSDPEGFLAHPVNAYKLMKRLNTEWSELESLVLQDPSDGFISNMSVHRQY---FPDEEDEKGA 131

  Fly   133 ALALVRLQSTYKLDVAQVAQGIL------NGVKYGSDMSWQDCFELGQQLFEMEDYNNTKVWLRE 191
            |.||:|||.|||||....::|.|      :||:|.:.::..|||::|:..:...||.::.:|:::
Zfish   132 AKALLRLQDTYKLDAESFSKGKLPGQRQHSGVRYNALLTVDDCFDMGKMAYNDNDYYHSVLWMQQ 196

  Fly   192 SMERLRRQTSHAPSHLAPTSGPDTVT--LNKMEATAKSLFQLGDFDTAFELSQRVLQFDP----- 249
            |:.::             .||.:..|  .:.::..:.|::|:||...|.||::|:|..||
Zfish   197 SLRQM-------------DSGEEAKTPKADVLDYLSYSVYQMGDLPRAIELTRRLLAIDPSHQRA 248

  Fly   250 -------KRIRNWHLGDKGTAPPEDIDDVYLPKHSDSYSLSQEF----AKYEKVCRGE-VHPIVR 302
                   :|:.:..|.|.|...||..|:  .|...|:|...:::    ..||.:|||| |....:
Zfish   249 GGNLRYFERLLSKELQDSGQTQPEPADE--RPIQLDTYQRPKDYLPEREAYEALCRGEGVKMTTK 311

  Fly   303 QELR--CRYSRGN-HPYRFLAPLKLEEHSLDPYVATFHDILSPGKISQLREMAVPRMHRSTVNPL 364
            ::.|  |||..|| :|...|.|:|.|:....|::..|.:.||..:|.:::|:|.|::.|:||...
Zfish   312 RQSRLFCRYRDGNRNPRLLLKPMKEEDEWDSPHIVRFLEALSDEEIQKIKEIATPKLARATVRDP 376

  Fly   365 PGGQLKKSAFRVSKNAWLAYESHPTMVGMLRDLKDATGLDTTFCEQLQVANYGVGGHYEPHWDFF 429
            ..|.|..:.:||||:|||..|..|.:..:.:.::|.|||.....|.||||||||||.||||:||.
Zfish   377 KTGVLTVAHYRVSKSAWLEGEDDPVIARVNQRIEDITGLTVDTAELLQVANYGVGGQYEPHFDFS 441

  Fly   430 R--DPNHYPA-EEGNRIATAIFYLSEVEQGGATAFPFLDIAVKPQLGNVLFWYNLHRSLDKDYRT 491
            |  :|:.:.: ..|||:||.:.|:|:||.||||.||....:|.|:.|..:|||||.||.:.||||
Zfish   442 RKDEPDAFKSLGTGNRVATYLNYMSDVEAGGATVFPDFGASVWPRKGTAVFWYNLFRSGEGDYRT 506

  Fly   492 KHAGCPVLKGSKWIGNVWIHEVTQTFARPC 521
            :||.||||.||||:.|.||||..|.|.|||
Zfish   507 RHAACPVLVGSKWVSNKWIHERGQEFRRPC 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE1	NP_733374.1	P4Ha_N	26..155	CDD:285528	49/131 (37%)
		P4Hc	341..511	CDD:214780	83/172 (48%)
p4ha2	XP_005173949.1	P4Ha_N	25..154	CDD:285528	49/131 (37%)
		P4Hc	353..526	CDD:214780	83/172 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52324
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.830