Protein Alignment PH4alphaNE1 and p4ha1b

DIOPT Version :9

• Sequence 1: NP_733374.1
• Gene: PH4alphaNE1 / 43625
• FlyBaseID: FBgn0039780
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_999856.1
• Gene: p4ha1b / 100003675
• ZFINID: ZDB-GENE-030131-4089
• Length: 536
• Species: Danio rerio
• Alignment Length: 542
• Identity: 200/542 - (36%)
• Similarity: 305/542 - (56%)
• Gaps: 57/542 - (10%)

  Fly    12 FLLAQGSLASDYFSSITGLEDLLHTEQYLTRELRSKVNAIQTALQQLESELSSIEKEHTMAASDT 76
            ||.|.    :|:|:|...:.|||:.|:.|...|:..:...:..|:|::.....::.....|..|.
Zfish    14 FLYAH----NDFFTSTGQMTDLLYAEKDLVTSLKEYIKQEENRLEQVKEWADKLDSLTITATQDP 74

  Fly    77 ENYLTNPVNVYRLMKRLHTDWSLMEGRVQLMAEE------MNFNATREYGLSYPSQEDVEGAALA 135
            |.:|.:|||.::|||||:::||.:|   .|:.::      .|....|:|   :|:.||..|||.|
Zfish    75 EGFLGHPVNAFKLMKRLNSEWSDLE---NLVLKDTTNGFISNLTVQRQY---FPTDEDQTGAAKA 133

  Fly   136 LVRLQSTYKLDVAQVAQGILNGVKYGSDMSWQDCFELGQQLFEMEDYNNTKVWLRESMERLRRQT 200
            |:|||.||:|....::.|.|.||.:.|.|:.:||:|||:..:...||.:|::|:.:::.:|..
Zfish   134 LLRLQDTYQLSANAISSGDLPGVVHKSRMTVEDCYELGKIAYSDADYYHTELWMAQALSQLDE-- 196

  Fly   201 SHAPSHLAPTSGPDTVTLNKMEATAKSLFQLGDFDTAFELSQRVLQFDPKRIR--------NWHL 257
                   ...|..|.||:  |:..:.:::|.|:.|.|.||::|:|:.||...|        .:.|
Zfish   197 -------GEESPIDKVTV--MDYLSYAIYQQGELDRALELTKRMLKLDPNHHRANGNLKYFEFQL 252

  Fly   258 GDKGTAPPE----------DIDDVYLPKHSDSYSLSQEFAKYEKVCRGE---VHPIVRQELRCRY 309
            ..:..|..|          |..|....:..|..   .|..|||::||||   :.|..:..|.|||
Zfish   253 EKQRKAENEKKEEDQKRVLDKRDAQRKRSKDPL---PERKKYERLCRGEGIKLTPRRQSRLFCRY 314

  Fly   310 SRGN-HPYRFLAPLKLEEHSLDPYVATFHDILSPGKISQLREMAVPRMHRSTV-NPLPGGQLKKS 372
            |..| :|...|||:|.|:....|.:..:|:|:|..:|..::|||.||:.|:|: ||:. |.|:.:
Zfish   315 SNNNRNPRLLLAPVKQEDEWDRPRIVRYHEIISDSEIETVKEMAKPRLRRATISNPIT-GVLETA 378

  Fly   373 AFRVSKNAWLAYESHPTMVGMLRDLKDATGLDTTFCEQLQVANYGVGGHYEPHWDFFR--DPNHY 435
            .:|:||:|||:...|.|:..:.:.::|.|||:....|:||||||||||.||||:||.|  :|:.:
Zfish   379 PYRISKSAWLSGYEHSTIERINQRIEDVTGLEMDTAEELQVANYGVGGQYEPHFDFGRKDEPDAF 443

  Fly   436 -PAEEGNRIATAIFYLSEVEQGGATAFPFLDIAVKPQLGNVLFWYNLHRSLDKDYRTKHAGCPVL 499
             ....||||||.:||:|:|..||||.|..:..||.|:.|..:|||||..|.:.||.|:||.||||
Zfish   444 KELGTGNRIATWLFYMSDVSAGGATVFTDVGAAVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVL 508

  Fly   500 KGSKWIGNVWIHEVTQTFARPC 521
            .|:||:.|.||||..|.|.|||
Zfish   509 VGNKWVSNKWIHERGQEFRRPC 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE1	NP_733374.1	P4Ha_N	26..155	CDD:285528	43/134 (32%)
		P4Hc	341..511	CDD:214780	83/173 (48%)
p4ha1b	NP_999856.1	P4Ha_N	24..153	CDD:285528	43/134 (32%)
		TPR repeat	164..199	CDD:276809	10/43 (23%)
		TPR_16	168..238	CDD:290168	23/80 (29%)
		TPR repeat	204..234	CDD:276809	11/31 (35%)
		P4Hc	347..520	CDD:214780	83/173 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52324
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.830