DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaMP and AT-P4H-1

DIOPT Version :9

Sequence 1:	NP_524594.2	Gene:	PH4alphaMP / 43624	FlyBaseID:	FBgn0026190	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_181836.1	Gene:	AT-P4H-1 / 818910	AraportID:	AT2G43080	Length:	283	Species:	Arabidopsis thaliana

Alignment Length:	216	Identity:	60/216 - (27%)
Similarity:	98/216 - (45%)	Gaps:	21/216 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   311 RLGYAPFKLEELHLDPLVVQLHQVIGSKDSDSLQKTARPRIKRSTVYSLGGNGGSTAAAFRTSQG 375
            |:|..  |.|.:...|.::.||..:..::.:.|:..||||::.|||..: ..|....:..|||.|
plant    71 RIGNV--KPEVVSWSPRIIVLHDFLSPEECEYLKAIARPRLQVSTVVDV-KTGKGVKSDVRTSSG 132

  Fly   376 ASFNYSRNA--ATKLLSRHVGDFSGLNMDYAEDLQVANYGIGGHYEPHWDSFPENHIYQEGDLHG 438
            ....:...:  ..:.:.:.:..||.:..:..|.:||..|.....|:||.|.|.:....:.|   |
plant   133 MFLTHVERSYPIIQAIEKRIAVFSQVPAENGELIQVLRYEPQQFYKPHHDYFADTFNLKRG---G 194

  Fly   439 NRMATGIYYLADVEAGGGTAFPFL-------------PLLVTPERGSLLFWYNLHPSGDQDFRTK 490
            .|:||.:.||.|...||.|.||..             .:.|.|.:|..:.::::...|..|.|:.
plant   195 QRVATMLMYLTDDVEGGETYFPLAGDGDCTCGGKIMKGISVKPTKGDAVLFWSMGLDGQSDPRSI 259

  Fly   491 HAACPVLQGSKWIANVWIRER 511
            |..|.||.|.||.|..|:|::
plant   260 HGGCEVLSGEKWSATKWMRQK 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaMP	NP_524594.2	P4Ha_N	24..156	CDD:285528
PH4alphaMP	NP_524594.2	P4Hc	336..509	CDD:214780	52/187 (28%)
AT-P4H-1	NP_181836.1	PLN00052	80..281	CDD:177683	56/205 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.920