DRSC/TRiP Functional Genomics Resources

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Protein Alignment PH4alphaMP and P4htm

DIOPT Version :9

Sequence 1:NP_524594.2 Gene:PH4alphaMP / 43624 FlyBaseID:FBgn0026190 Length:535 Species:Drosophila melanogaster
Sequence 2:NP_083220.3 Gene:P4htm / 74443 MGIID:1921693 Length:503 Species:Mus musculus


Alignment Length:353 Identity:89/353 - (25%)
Similarity:135/353 - (38%) Gaps:113/353 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   231 LVNHVLSIEPDQRSHLLEARQQLEELITDGDKNGLLHLTARRPGDYHESREFRMYEQVCRGELAP 295
            |:.|:..::..|||.:|                         |.:.:|.....|  ||.:.:|..
Mouse   159 LIIHLAQMKGLQRSQIL-------------------------PTEEYEEAMSAM--QVSQLDLFQ 196

  Fly   296 LPSKQRNLRCRLR----KSRLG----YAPFKLEELH----LDPLVVQLHQVIGSKDSD---SLQK 345
            |..:..:.|.:||    ::|||    ..|..::|::    .||            |.|   |||:
Mouse   197 LLDQNHDGRLQLREVLAQTRLGNGRWMTPENIQEMYSAIKADP------------DGDGVLSLQE 249

  Fly   346 TARPRIKRSTVYSLGGNGGSTAAAFRTS------QGASFNYSRNAATKLLSRHVGDFSGLNMDYA 404
            .:...::....| :..:...:....|.|      ||...::...|..:.:.| :...|...::::
Mouse   250 FSNMDLRDFHKY-MRSHKAESNELVRNSHHTWLHQGEGAHHVMRAIRQRVLR-LTRLSPEIVEFS 312

  Fly   405 EDLQVANYGIGGHYEPHWDS---FPENHIYQEGDLHGN---------RMATGIYYLADVEAGGGT 457
            |.|||..||.||||..|.||   :||. |.....|..|         |..|.::||.:|..||.|
Mouse   313 EPLQVVRYGEGGHYHAHVDSGPVYPET-ICSHTKLVANESVPFETSCRYMTVLFYLNNVTGGGET 376

  Fly   458 AFPFLP---------------------------LLVTPERGSLLFWYNLHPS-----GDQDFRTK 490
            .||...                           |.|.|::|:.:||||..|.     |:.|..:.
Mouse   377 VFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQQGTAVFWYNYLPDGQGWVGEVDDYSL 441

  Fly   491 HAACPVLQGSKWIANVWIRERNQDNVRP 518
            |..|.|.:|:|||||.||      ||.|
Mouse   442 HGGCLVTRGTKWIANNWI------NVDP 463

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PH4alphaMPNP_524594.2 P4Ha_N 24..156 CDD:285528
P4Hc 336..509 CDD:214780 62/225 (28%)
P4htmNP_083220.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..49
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 90..110
EF-hand_7 193..253 CDD:290234 17/71 (24%)
EFh 195..253 CDD:298682 16/69 (23%)
P4Hc 247..459 CDD:214780 58/214 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167839378
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1591
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.740

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