DRSC/TRiP Functional Genomics Resources

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Protein Alignment PH4alphaMP and P4htm

DIOPT Version :10

Sequence 1:NP_524594.2 Gene:PH4alphaMP / 43624 FlyBaseID:FBgn0026190 Length:535 Species:Drosophila melanogaster
Sequence 2:NP_083220.3 Gene:P4htm / 74443 MGIID:1921693 Length:503 Species:Mus musculus


Alignment Length:353 Identity:89/353 - (25%)
Similarity:135/353 - (38%) Gaps:113/353 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   231 LVNHVLSIEPDQRSHLLEARQQLEELITDGDKNGLLHLTARRPGDYHESREFRMYEQVCRGELAP 295
            |:.|:..::..|||.:|                         |.:.:|.....|  ||.:.:|..
Mouse   159 LIIHLAQMKGLQRSQIL-------------------------PTEEYEEAMSAM--QVSQLDLFQ 196

  Fly   296 LPSKQRNLRCRLR----KSRLG----YAPFKLEELH----LDPLVVQLHQVIGSKDSD---SLQK 345
            |..:..:.|.:||    ::|||    ..|..::|::    .||            |.|   |||:
Mouse   197 LLDQNHDGRLQLREVLAQTRLGNGRWMTPENIQEMYSAIKADP------------DGDGVLSLQE 249

  Fly   346 TARPRIKRSTVYSLGGNGGSTAAAFRTS------QGASFNYSRNAATKLLSRHVGDFSGLNMDYA 404
            .:...::....| :..:...:....|.|      ||...::...|..:.:.| :...|...::::
Mouse   250 FSNMDLRDFHKY-MRSHKAESNELVRNSHHTWLHQGEGAHHVMRAIRQRVLR-LTRLSPEIVEFS 312

  Fly   405 EDLQVANYGIGGHYEPHWDS---FPENHIYQEGDLHGN---------RMATGIYYLADVEAGGGT 457
            |.|||..||.||||..|.||   :||. |.....|..|         |..|.::||.:|..||.|
Mouse   313 EPLQVVRYGEGGHYHAHVDSGPVYPET-ICSHTKLVANESVPFETSCRYMTVLFYLNNVTGGGET 376

  Fly   458 AFPFLP---------------------------LLVTPERGSLLFWYNLHPS-----GDQDFRTK 490
            .||...                           |.|.|::|:.:||||..|.     |:.|..:.
Mouse   377 VFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQQGTAVFWYNYLPDGQGWVGEVDDYSL 441

  Fly   491 HAACPVLQGSKWIANVWIRERNQDNVRP 518
            |..|.|.:|:|||||.||      ||.|
Mouse   442 HGGCLVTRGTKWIANNWI------NVDP 463

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PH4alphaMPNP_524594.2 P4Ha_N 24..158 CDD:462433
P4Hc 336..509 CDD:214780 62/225 (28%)
P4htmNP_083220.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..49
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 90..110
EF-hand_7 193..253 CDD:463900 17/71 (24%)
P4Hc 247..459 CDD:214780 58/214 (27%)
Blue background indicates that the domain is not in the aligned region.

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