Protein Alignment PH4alphaMP and p4ha1a

DIOPT Version :10

• Sequence 1: NP_524594.2
• Gene: PH4alphaMP / 43624
• FlyBaseID: FBgn0026190
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_073773811.1
• Gene: p4ha1a / 562774
• ZFINID: ZDB-GENE-040724-91
• Length: 603
• Species: Danio rerio
• Alignment Length: 559
• Identity: 187/559 - (33%)
• Similarity: 302/559 - (54%)
• Gaps: 75/559 - (13%)

  Fly     9 FLVLQVL---SCHGEFFSSTSGLAKLFETEVVLLAELQNYV-------NEINQHAEALQSEIDAI 63
            ||::.:|   |.|.:||:|...:..|..||..|:..|::|:       .::.|.||    ::||:
Zfish    72 FLLISLLKSSSAHSDFFTSIGHMTDLLFTEKDLVTSLKDYIKAEESKLEQVKQWAE----KLDAL 132

  Fly    64 RVEHLNAADGIDDYLNNPVNAFRLIKRLHSDWETFEGSVTADSSRSNYLDTMASLKENLSFPSQD 128
            ....:...:|   :|.:|||||:|:|||:::|...|..|..|.| ..::..:...::  .||:.:
Zfish   133 TATAVQDPEG---FLGHPVNAFKLMKRLNTEWGEVEDLVLKDMS-DGFISNLTIQRQ--YFPNDE 191

  Fly   129 DFVGSAIALTRLQQTYQLDVAELASGILNGVK----YGTAMSWQDCFVLGQHLYALRDYNHTVPW 189
            |..|:|.||.|||.||:||...::||.|.||.    |.:.::.:|||.||:..|:..||.||..|
Zfish   192 DQNGAAKALLRLQDTYKLDTQTISSGDLPGVNTGLPYKSTLTVEDCFELGKIAYSDADYYHTELW 256

  Fly   190 LQQSMQLL--GEQSYGSESASLDFMEAVVEYHREMGAHESALSLVNHVLSIEPD----------- 241
            :.|:::.|  ||:|....:.:||::...|   .:.|..|.||.....:|::||:
Zfish   257 MAQALKQLDEGEESSVEIATALDYLSYSV---YQQGELERALEYTKRLLTVEPEHQRALGNLKYF 318

  Fly   242 ----------QRSHLLEARQQLEELITDGDKNGLLHLTARRPGDYHESREFRMYEQVCRGE-LAP 295
                      ::....:...:.|:..:||.|..|              .|.|.||::|||| |..
Zfish   319 DYQLAKQKKAEKEQSTKEESKKEQETSDGKKEYL--------------PEKRKYEKLCRGEGLRM 369

  Fly   296 LPSKQRNLRCRL----RKSRLGYAPFKLEELHLDPLVVQLHQVIGSKDSDSLQKTARPRIKRSTV 356
            .|.:|::|.||.    |.......|.|.|:....|.:::.|::|..::.:.:::.::||::|:|:
Zfish   370 TPRRQKHLFCRYFNGNRHPFYTIGPVKQEDEWDRPRIIRYHEIITEQEIEKIKELSKPRLRRATI 434

  Fly   357 YSLGGNGGSTAAAFRTSQGASFNYSRNAATKLLSRHVGDFSGLNMDYAEDLQVANYGIGGHYEPH 421
             |....|....|.:|.|:.|......:.....:::.:.|.:|||:..||:|||||||:||.||||
Zfish   435 -SNPITGVLETAHYRISKSAWLAAYEHPVVDRINQRIEDITGLNVKTAEELQVANYGVGGQYEPH 498

  Fly   422 WD--SFPENHIYQE-GDLHGNRMATGIYYLADVEAGGGTAFPFLPLLVTPERGSLLFWYNLHPSG 483
            :|  ...|...::| |.  |||:||.::|::||.|||.|.||.:...|.|.:|:.:|||||.|||
Zfish   499 FDFGRKDEPDAFKELGT--GNRIATWLFYMSDVAAGGATVFPEVGAAVKPLKGTAVFWYNLFPSG 561

  Fly   484 DQDFRTKHAACPVLQGSKWIANVWIRERNQDNVRPCDLE 522
            :.|:.|:|||||||.|:||::|.||.||.|:..|||.|:
Zfish   562 EGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCGLK 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaMP	NP_524594.2	P4Ha_N	24..158	CDD:462433	45/140 (32%)
		P4Hc	336..509	CDD:214780	72/175 (41%)
p4ha1a	XP_073773811.1	None