Protein Alignment PH4alphaMP and P4HTM

DIOPT Version :9

• Sequence 1: NP_524594.2
• Gene: PH4alphaMP / 43624
• FlyBaseID: FBgn0026190
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_808807.2
• Gene: P4HTM / 54681
• HGNCID: 28858
• Length: 563
• Species: Homo sapiens
• Alignment Length: 443
• Identity: 96/443 - (21%)
• Similarity: 145/443 - (32%)
• Gaps: 189/443 - (42%)

  Fly   225 HESALSLVN------HVLSIEPDQRSHLLEARQQLEELITDGDKNGLLHLTARRPG--------- 274
            ||..:.||.      ..||::|     ||   .::...:||.:...::|| |:..|
Human   121 HERKVQLVTDRDHFIRTLSLKP-----LL---FEIPGFLTDEECRLIIHL-AQMKGLQRSQILPT 176

  Fly   275 -DYHESRE---------FRMYEQVCRGELAPLPSKQRNLRCRLRKSRLG----YAPFKLEELH-- 323
             :|.|:..         ||:.:|...|.|        .||..|.::|||    ..|..::|::
Human   177 EEYEEAMSTMQVSQLDLFRLLDQNRDGHL--------QLREVLAQTRLGNGWWMTPESIQEMYAA 233

  Fly   324 --LDPLVVQLHQVIGSKDSD---SLQKTARPRIKRSTVYSLGGNGGSTAAAFRTS------QGAS 377
              .||            |.|   |||:.:...::....| :..:...::...|.|      ||..
Human   234 IKADP------------DGDGVLSLQEFSNMDLRDFHKY-MRSHKAESSELVRNSHHTWLYQGEG 285

  Fly   378 FNYSRNAATKLLSRHVGDFSGLNMDYAEDLQVANYGIGGHYEPHWDSFPENHIYQEGDLHGNRMA 442
            .::...|..:.:.| :...|...::.:|.|||..||.||||..|.||.|   :|.|......::.
Human   286 AHHIMRAIRQRVLR-LTRLSPEIVELSEPLQVVRYGEGGHYHAHVDSGP---VYPETICSHTKLV 346

  Fly   443 ----------------------------------------------------------------- 442
                                                                             
Human   347 ANESVPFETSCRQVSPNWGLPSILRPGTPMTQAQPCTVGVPLGMGPGDHWVIPVSPWEHPQLGTC 411

  Fly   443 ----------TGIYYLADVEAGGGTAFPFLP---------------------------LLVTPER 470
                      |.::||.:|..||.|.||...                           |.|.|::
Human   412 SVPPLPYSYMTVLFYLNNVTGGGETVFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQQ 476

  Fly   471 GSLLFWYNLHPS-----GDQDFRTKHAACPVLQGSKWIANVWIRERNQDNVRP 518
            |:.:||||..|.     ||.|..:.|..|.|.:|:|||||.||      ||.|
Human   477 GTAVFWYNYLPDGQGWVGDVDDYSLHGGCLVTRGTKWIANNWI------NVDP 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaMP	NP_524594.2	P4Ha_N	24..156	CDD:285528
		P4Hc	336..509	CDD:214780	60/288 (21%)
P4HTM	NP_808807.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..111
		EF-hand_7	192..252	CDD:290234	20/79 (25%)
		EFh	194..252	CDD:238008	20/77 (26%)
		P4Hc	246..519	CDD:214780	56/277 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149320
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740