Protein Alignment PH4alphaMP and LOC4577387

DIOPT Version :10

• Sequence 1: NP_524594.2
• Gene: PH4alphaMP / 43624
• FlyBaseID: FBgn0026190
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_001237637.4
• Gene: LOC4577387 / 4577387
• VectorBaseID: AGAMI1_013198
• Length: 514
• Species: Anopheles gambiae
• Alignment Length: 537
• Identity: 190/537 - (35%)
• Similarity: 280/537 - (52%)
• Gaps: 46/537 - (8%)

  Fly     4 AKCVLFLVLQVLSC-------HGEFFSSTSGLAKLFETEVVLLAELQNYVNEINQHAEALQSEID 61
            ||...|.:...|.|       |||::||...:.||.:.|..|:|.|..|:....|..|.|..:.|
Mosquito     3 AKLFFFAIGWWLCCYHPWTNVHGEYYSSVEQMRKLLKLEESLVASLGQYIKLHEQKIEFLHRQRD 67

  Fly    62 AIRVEHLNAADGIDDYLNNPVNAFRLIKRLHSDWETFEGSVTADSSRSNYLDTMASLKENLSFPS 126
            .:..|.........:|.:|||:||.::.||.:|||.....:.        :|..|.|:.....|:
Mosquito    68 LLEKELKKGLKDDIEYSSNPVSAFLMVNRLVNDWERLRAFMD--------MDVGAKLQNTTEMPT 124

  Fly   127 QDDFVGSAIALTRLQQTYQLDVAELASGILNGVKYGTAMSWQDCFVLGQHLYALRDYNHTVPWLQ 191
            .:|.:|....|.|||..|:|:..|:|||.|.....|..:...:|:.:|..|.|.:.|.|.|.||:
Mosquito   125 HEDLIGVVEGLARLQDMYELNAKEMASGKLLDRTIGRQLKTAECYEIGNKLTAAKSYRHAVSWLR 189

  Fly   192 QSMQLLGEQSYGSESASLDFMEAVVEYHREMGAHESALSLVNHVLSIEPD-QRSHLLEARQQLEE 255
            :|::|....|.|  .:.::.|.|:.......|.:|.||.|...||.::|| ||:  |.:::.||:
Mosquito   190 ESLRLWTMDSPG--VSKVEVMNALSYALSHQGEYEEALELTQKVLKLQPDNQRA--LNSKEPLEK 250

  Fly   256 LITDGDKNGLLHLTARRPGDYHESREFRMYEQVCRGELAPLPSKQ-RNLRCRLRKSR---LGYAP 316
            .|....::|   |....|..|     .:.|..:|||: ...|:|: ..||||...:|   |..:|
Mosquito   251 WIEYKKQHG---LPPPVPEPY-----VKNYPSLCRGD-DQRPAKELAKLRCRYEHNRTPFLRISP 306

  Fly   317 FKLEELHLDPLVVQLHQVIGSKDSDSLQKTARPRIKRSTVYSLGGNGGSTAAAFRTSQGASFNYS 381
            .||:|::.||::|..|.||.:|:.|::...::|.:.||.|   |.:.....:..|||..|..:..
Mosquito   307 LKLQEVNHDPMIVMYHDVISNKEIDAIISISKPLMHRSMV---GDDHEKAVSKTRTSSNAWLDDV 368

  Fly   382 RNAATKLLSRHVGDFSGLNMDYAEDLQVANYGIGGHYEPHWDSFPENHIYQEG-DLH-----GNR 440
            .:...:.||:...|.:.|.|..||.|||.||||||||.||:|    ..:.:|| :::     |||
Mosquito   369 MHPVVRTLSQRTEDMTNLAMTAAERLQVGNYGIGGHYLPHYD----YAVAEEGKEVYPSIGKGNR 429

  Fly   441 MATGIYYLADVEAGGGTAFPFLPLLVTPERGSLLFWYNLHPSGDQDFRTKHAACPVLQGSKWIAN 505
            :||.:|||:||..||.|.||.|.|.|.|::||.:||||||.:|..|.||.|.||||..||||:.|
Mosquito   430 IATVMYYLSDVAIGGATVFPQLGLGVFPQKGSAIFWYNLHANGTVDHRTLHGACPVFVGSKWVGN 494

  Fly   506 VWIRERNQDNVRPCDLE 522
            .||.||.|:..|.|:|:
Mosquito   495 KWIHERGQEFRRSCELD 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaMP	NP_524594.2	P4Ha_N	24..158	CDD:462433	41/133 (31%)
		P4Hc	336..509	CDD:214780	76/178 (43%)
LOC4577387	XP_001237637.4	None