Protein Alignment PH4alphaMP and PH4alphaNE1

DIOPT Version :10

• Sequence 1: NP_524594.2
• Gene: PH4alphaMP / 43624
• FlyBaseID: FBgn0026190
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_733374.1
• Gene: PH4alphaNE1 / 43625
• FlyBaseID: FBgn0039780
• Length: 537
• Species: Drosophila melanogaster
• Alignment Length: 558
• Identity: 244/558 - (43%)
• Similarity: 329/558 - (58%)
• Gaps: 55/558 - (9%)

  Fly     1 MLLAKCVLFLVLQVLSCHGEFFSSTSGLAKLFETEVVLLAELQNYVNEINQHAEALQSEIDAIRV 65
            ::|...::||:.|. |...::|||.:||..|..||..|..||::.||.|....:.|:||:.:|..
  Fly     4 LVLLVGLIFLLAQG-SLASDYFSSITGLEDLLHTEQYLTRELRSKVNAIQTALQQLESELSSIEK 67

  Fly    66 EHLNAADGIDDYLNNPVNAFRLIKRLHSDWETFEGSVTADSSRSNYLDTMASLKENLSFPSQDDF 130
            ||..||...::||.||||.:||:||||:||...||.|...:...|:   .|:.:..||:|||:|.
  Fly    68 EHTMAASDTENYLTNPVNVYRLMKRLHTDWSLMEGRVQLMAEEMNF---NATREYGLSYPSQEDV 129

  Fly   131 VGSAIALTRLQQTYQLDVAELASGILNGVKYGTAMSWQDCFVLGQHLYALRDYNHTVPWLQQSMQ 195
            .|:|:||.|||.||:||||::|.|||||||||:.|||||||.|||.|:.:.|||:|..||::||:
  Fly   130 EGAALALVRLQSTYKLDVAQVAQGILNGVKYGSDMSWQDCFELGQQLFEMEDYNNTKVWLRESME 194

  Fly   196 LLGEQ----------SYGSESASLDFMEAVVEYHREMGAHESALSLVNHVLSIEPD--QRSHLLE 248
            .|..|          :.|.::.:|:.|||..:...::|..::|..|...||..:|.  :..||
  Fly   195 RLRRQTSHAPSHLAPTSGPDTVTLNKMEATAKSLFQLGDFDTAFELSQRVLQFDPKRIRNWHL-- 257

  Fly   249 ARQQLEELITDGDKNGLLHLTA-----------RRPGDYHESREFRMYEQVCRGELAPLPSKQRN 302
                       |||.     ||           :....|..|:||..||:|||||:.|:  .::.
  Fly   258 -----------GDKG-----TAPPEDIDDVYLPKHSDSYSLSQEFAKYEKVCRGEVHPI--VRQE 304

  Fly   303 LRCRLRKSRLGY---APFKLEELHLDPLVVQLHQVIGSKDSDSLQKTARPRIKRSTVYSLGGNGG 364
            ||||..:....|   ||.||||..|||.|...|.::.......|::.|.||:.||||..|.| |.
  Fly   305 LRCRYSRGNHPYRFLAPLKLEEHSLDPYVATFHDILSPGKISQLREMAVPRMHRSTVNPLPG-GQ 368

  Fly   365 STAAAFRTSQGASFNYSRNAATKLLSRHVGDFSGLNMDYAEDLQVANYGIGGHYEPHWDSFPE-N 428
            ...:|||.|:.|...|..:.....:.|.:.|.:||:..:.|.|||||||:|||||||||.|.: |
  Fly   369 LKKSAFRVSKNAWLAYESHPTMVGMLRDLKDATGLDTTFCEQLQVANYGVGGHYEPHWDFFRDPN 433

  Fly   429 HIYQEGDLHGNRMATGIYYLADVEAGGGTAFPFLPLLVTPERGSLLFWYNLHPSGDQDFRTKHAA 493
            |...|   .|||:||.|:||::||.||.||||||.:.|.|:.|::|||||||.|.|:|:|||||.
  Fly   434 HYPAE---EGNRIATAIFYLSEVEQGGATAFPFLDIAVKPQLGNVLFWYNLHRSLDKDYRTKHAG 495

  Fly   494 CPVLQGSKWIANVWIRERNQDNVRPCDLERGQEISLHY 531
            ||||:|||||.||||.|..|...||||:.|..|:||.|
  Fly   496 CPVLKGSKWIGNVWIHEVTQTFARPCDVFRDHEVSLEY 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaMP	NP_524594.2	P4Ha_N	24..158	CDD:462433	62/133 (47%)
		P4Hc	336..509	CDD:214780	90/173 (52%)
PH4alphaNE1	NP_733374.1	P4Ha_N	26..157	CDD:462433	62/133 (47%)
		P4Hc	341..511	CDD:214780	90/173 (52%)