Protein Alignment PH4alphaMP and CG4174

DIOPT Version :9

• Sequence 1: NP_524594.2
• Gene: PH4alphaMP / 43624
• FlyBaseID: FBgn0026190
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001034031.2
• Gene: CG4174 / 40023
• FlyBaseID: FBgn0036793
• Length: 473
• Species: Drosophila melanogaster
• Alignment Length: 524
• Identity: 125/524 - (23%)
• Similarity: 230/524 - (43%)
• Gaps: 80/524 - (15%)

  Fly     7 VLFLVLQVLSC-----HGEFFSSTSG--LAKLFETEVVLLAELQNYVNEINQHAEALQSEIDAIR 64
            :||..:.|.:|     .||..|:...  .|...|:::.||...:.:||.:..:.:.|:..:..||
  Fly     1 MLFHFVVVTACLGFQVKGEVVSAPESYDFAISSESQLSLLKLKETHVNNLQSYKKVLKKHLQKIR 65

  Fly    65 VEHLNAADGIDDYLNNPVN---AFRLIKRLHSDWETFEGSVTADSSRSNYLDTMASLKENLSFPS 126
            .....:.:.:.....:|.|   .:::::.||:||..:...:..|........:...|.:.   |:
  Fly    66 RAIRQSEELLKSTKTSPRNLIYGYKVLRHLHNDWPQYFRLLKKDLGLEQIAVSQMLLTQQ---PT 127

  Fly   127 QDDFVGSAIALTRLQQTYQLDVAELASGILNGVKYGTAMSW--QDCFVLGQHLYALRDYNHTVPW 189
            ..||..|..|:.|||..|.||...:..|.::. |.....:|  .:|.:||.....|:|||.:..|
  Fly   128 SVDFEESMGAMHRLQTVYNLDSYAMTEGFIDD-KDKNIRNWSADECLMLGLMYLFLKDYNQSENW 191

  Fly   190 LQQSMQLLGEQSYGSESASL------DFMEAVVEYHREMGAHESALSLVNHVLSIEPDQRSHLLE 248
            |:.::... :.:...|...:      :.:|::||.::.:|.:..|....|.:|||.|: .:::|.
  Fly   192 LELALYHY-DDNVSPEVLKIKLWNYPNLLESLVEANKGLGHYFEAKKYANELLSINPN-HTYMLT 254

  Fly   249 ARQQLEELITDGDKNGLLHLTARRPGDYHESREFRMYEQVCRGELAPLPSKQRNLRCRLRKSR-- 311
            ...:|:.|.::..|     ||  :|     .:.|::.:::|        ||:...:..:...|
  Fly   255 QLPKLKHLQSNPAK-----LT--KP-----KKVFQLQKEIC--------SKRYRRKSGVLVCRYV 299

  Fly   312 -----LGYAPFKLEELHLDPLVVQLHQVIGSKDSDSLQKTARPRIKRSTVYSLGGNGGSTAAAFR 371
                 |..||.|:|||.:.|.:...:..:|.||.:.|:..:||:::|  :..|.||.........
  Fly   300 DWTPFLKLAPLKMEELSMKPYISIFYGFLGQKDIEVLKNVSRPKLQR--IEHLSGNCSCKIGNLS 362

  Fly   372 TSQGASFNYSRNAATKLLSRHVGDFSGLNMDYAEDLQVANYGIGGHYEPHWDSFPENHIYQEGDL 436
            |        |.:...:.::..:...:|..:...:.|:|.||||.|:|.|           :|..:
  Fly   363 T--------SLHDVVRKVNELILGITGFPLKGNQMLEVINYGIAGNYNP-----------EEPKI 408

  Fly   437 HGNRMATGIYYLADVEAGGGTAFPFLPLLVTPERGSLLFWYNLHPSGDQDFRTKHAACPVLQGSK 501
            |..  |....:|::...||...||...|.|.|.:||:|.|.||..|      ..:..||:|:|:.
  Fly   409 HNK--ANAFIFLSNAGKGGEIVFPSRHLKVRPRKGSMLVWENLKKS------LIYHQCPILKGNM 465

  Fly   502 WIAN 505
            |:||
  Fly   466 WVAN 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaMP	NP_524594.2	P4Ha_N	24..156	CDD:285528	29/136 (21%)
		P4Hc	336..509	CDD:214780	47/170 (28%)
CG4174	NP_001034031.2	P4Ha_N	33..157	CDD:285528	28/126 (22%)
		TPR repeat	169..197	CDD:276809	9/27 (33%)
		TPR repeat	202..245	CDD:276809	8/42 (19%)
		2OG-FeII_Oxy	<362..470	CDD:304390	37/135 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461869
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.990