Protein Alignment PH4alphaMP and P4ha3

DIOPT Version :9

• Sequence 1: NP_524594.2
• Gene: PH4alphaMP / 43624
• FlyBaseID: FBgn0026190
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_038938408.1
• Gene: P4ha3 / 361612
• RGDID: 735150
• Length: 549
• Species: Rattus norvegicus
• Alignment Length: 514
• Identity: 156/514 - (30%)
• Similarity: 248/514 - (48%)
• Gaps: 70/514 - (13%)

  Fly    22 FSSTSGLAKLFETEVVLLAELQNYVNEINQHAEALQSEIDAIRVEHLNAADGIDDYLNNPVNAFR 86
            ||:.:.:|:....|..||..|:.|:    :..||...::.....:.|:..:.:...:.||:.||.
  Rat    31 FSALTSVARALAPERRLLGTLRRYL----RGEEARLRDLTRFYDKVLSLHEDLKIPVVNPLLAFT 91

  Fly    87 LIKRLHSDWETFEGSVTADSSRSNYLDTMASLKENLSFPSQDDFVGSAIALTRLQQTYQLDVAEL 151
            |||||.|||.....|:.|..:.....|....::::|  |:.:|..|:|.||.|||..|.|:|..|
  Rat    92 LIKRLQSDWRNVVHSLEATENIRALKDGYEKVEQDL--PAFEDLEGAARALMRLQDVYMLNVKGL 154

  Fly   152 ASGILNGVKYGT-----------AMSWQDCFVLGQHLYALRDYNHTVPWLQQSMQLLGEQSYG-- 203
            |.|:...|...:           :::..|||.:|:..|...||.|.:|||::::.|. .:|||
  Rat   155 AQGVFQRVTGSSITDLYSPRQLFSLTADDCFQVGKVAYDTGDYYHAIPWLEEAVSLF-RRSYGEW 218

  Fly   204 --SESASL-DFMEAVVEYHREMGAHESALSLVNHVLSIEPDQRSHLLEARQQL--EELITDGDKN 263
              .:.||| |.::.:.....::|....||||....|...||.:.   .||..|  |.|:.:   |
  Rat   219 KTEDEASLEDALDYLAFACYQVGNVSCALSLSREFLVYSPDNKR---MARNVLKYERLLAE---N 277

  Fly   264 GLLHLTA-----RRPGDYH-ESREFRMYEQVCRGELAPLPSKQR--NLRCRLRKSRLGY---APF 317
            |  ||.|     :||...| ::|:  .||.:|: .|...|:..:  :|.|....:...|   .|.
  Rat   278 G--HLMAAETAIQRPNVPHLQTRD--TYEGLCQ-TLGSQPTHYQIPSLYCSYETNSSPYLLLQPA 337

  Fly   318 KLEELHLDPLVVQLHQVIGSKDSDSLQKTARPRIKRSTVYSLGGNGGSTAAAFRTSQGASFNYSR 382
            :.|.:||.|||...|..:..:::..:::.|.|.::||.|.|   ........:|.|:.|....:.
  Rat   338 RKEVIHLRPLVALYHDFVSDEEAQKIRELAEPWLQRSVVAS---GEKQLQVEYRISKSAWLKDTV 399

  Fly   383 NAATKLLSRHVGDFSGLNMD--YAEDLQVANYGIGGHYEPHWD--SFPENHIYQEGDLHGNRMAT 443
            :.....|.|.:...:||::.  |||.|||.|||||||||||:|  :.|.:.:|:...  |||:||
  Rat   400 DPVLVTLDRRIAALTGLDIQPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYKMKS--GNRVAT 462

  Fly   444 GIYYLADVEAGGGTAFPF----LPLLVTPERGSLLFWYNLHPSGDQDFRTKHAACPVLQ 498
            .:.||:.|||||.|||.:    :|::..|..|     |.     ..|..::..|.|:|:
  Rat   463 LMIYLSSVEAGGATAFIYGNFSVPVVKWPTSG-----YT-----SMDRNSEDPAAPILK 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaMP	NP_524594.2	P4Ha_N	24..156	CDD:285528	40/131 (31%)
		P4Hc	336..509	CDD:214780	56/171 (33%)
P4ha3	XP_038938408.1	P4Ha_N	34..108	CDD:400573	22/77 (29%)
		P4Hc	356..>478	CDD:214780	46/126 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343167
Domainoid	1	1.000	63	1.000	Domainoid score	I9991
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52324
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.760