Protein Alignment PH4alphaMP and PH4alphaSG1

DIOPT Version :9

• Sequence 1: NP_524594.2
• Gene: PH4alphaMP / 43624
• FlyBaseID: FBgn0026190
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_733376.1
• Gene: PH4alphaSG1 / 326112
• FlyBaseID: FBgn0051014
• Length: 540
• Species: Drosophila melanogaster
• Alignment Length: 554
• Identity: 196/554 - (35%)
• Similarity: 294/554 - (53%)
• Gaps: 47/554 - (8%)

  Fly     7 VLFLVLQVLSCHGEFFSSTSGLAKLFETEVVLLAELQNYVNEINQHAEALQSEIDAIRVEHLNAA 71
            ::..:|.|...:|:::|:.|.|.:|.:.|..::.:...|:....|..|.|:..:|.|. |..|..
  Fly     6 IILSLLCVFPVNGDYYSAISELERLLDVEAFIVEKFDEYLERAQQEQENLKRFLDQID-EQQNDR 69

  Fly    72 DGIDDYLNNPVNAFRLIKRLHSDWETFEGSVTADSSR-SNYLDTMASLKENLSF--PSQDDFVGS 133
            ..:::|..||:|||..||||..||:........|||. ..|.:.::...|.::|  |:|:|..|:
  Fly    70 GDLEEYFGNPINAFITIKRLVHDWKFNVFDPVFDSSNFETYKNNLSDSLEKINFKGPTQEDLHGA 134

  Fly   134 AIALTRLQQTYQLDVAELASGILN-GVK--YGTAMSWQDCFVLGQHLYALRDYNHTVPWLQQSMQ 195
            ..||.|||..|||:...||||:|: |.|  .||::|..|||.||::|..:::|::...||.::.:
  Fly   135 TRALLRLQNMYQLNTDHLASGVLHPGEKNALGTSLSASDCFELGKNLCEIKEYSYGSEWLLEARK 199

  Fly   196 LLGEQSYGSES---ASLDFMEAVVEYHREMGAHESALSLVNHVLSIEPDQRSHLLEARQQLEELI 257
            .|..:..|..|   :.::.:|.:......:|..:.|..|.|.:|..:||....|
  Fly   200 RLHGKPLGFISPNVSDVEILEHLSSAFNGLGNLKLAYKLNNEILDKKPDHEEAL----------- 253

  Fly   258 TDGDKNGLLH---LTARRP------------GDYHESREFRMYEQVCRGELAPLPSKQRNLRCRL 307
                ||.:|:   |...|.            .:..:...:::|.|||||||...|.:||||||.|
  Fly   254 ----KNKILYEGQLARERSFAPRKQVELPQIAEKEQKESYKLYTQVCRGELHQSPREQRNLRCWL 314

  Fly   308 RKSRLGY---APFKLEELHLDPLVVQLHQVIGSKDSDSLQKTARPRIKRSTVYSLGGNGGSTAAA 369
            ....:.|   :|||:|:|::||.|..:|:|:...:.|::.:..:..::||.|   |.:..||.:.
  Fly   315 YHQGVPYYRLSPFKIEQLNVDPYVAYVHEVLWDSEIDTIMEHGKGNMERSKV---GQSENSTTSE 376

  Fly   370 FRTSQGASFNYSRNAATKLLSRHVGDFSGLNMDYAEDLQVANYGIGGHYEPHWDSFPENHIYQEG 434
            .|.|:.....|..|.....:.:.:.|.:||:.:.||.||:.||||||.||||:| |.|:......
  Fly   377 VRISRNTWLWYDANPWLSKIKQRLEDVTGLSTESAEPLQLVNYGIGGQYEPHFD-FVEDDGQSVF 440

  Fly   435 DLHGNRMATGIYYLADVEAGGGTAFPFLPLLVTPERGSLLFWYNLHPSGDQDFRTKHAACPVLQG 499
            ...|||:.|.::||.||..||.||||||.|.|.|.:||||.|||||.|..:|||||||.||||||
  Fly   441 SWKGNRLLTALFYLNDVALGGATAFPFLRLAVPPVKGSLLIWYNLHSSTHKDFRTKHAGCPVLQG 505

  Fly   500 SKWIANVWIRERNQDNVRPCDLERGQEISLHYRD 533
            ||||.|.|.....|:..|||.|...:...||.:|
  Fly   506 SKWICNEWFHVGAQEFRRPCGLSSDEGKFLHLKD 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaMP	NP_524594.2	P4Ha_N	24..156	CDD:285528	46/134 (34%)
		P4Hc	336..509	CDD:214780	79/172 (46%)
PH4alphaSG1	NP_733376.1	P4Ha_N	23..157	CDD:285528	46/134 (34%)
		P4Hc	347..515	CDD:214780	79/171 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461959
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	10	9.900