Protein Alignment PH4alphaMP and P4ha3

DIOPT Version :9

• Sequence 1: NP_524594.2
• Gene: PH4alphaMP / 43624
• FlyBaseID: FBgn0026190
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_006508007.1
• Gene: P4ha3 / 320452
• MGIID: 2444049
• Length: 551
• Species: Mus musculus
• Alignment Length: 534
• Identity: 168/534 - (31%)
• Similarity: 259/534 - (48%)
• Gaps: 53/534 - (9%)

  Fly    22 FSSTSGLAKLFETEVVLLAELQNYVNEINQHAEALQSEIDAIRVEHLNAADGIDDYLNNPVNAFR 86
            ||:.:.:|:....|..||..|:.|:    :..||...::.....:.|:..:.:...:.||:.||.
Mouse    29 FSALTSVARALAPERRLLGTLRRYL----RGEEARLRDLTRFYDKVLSLHEDLKIPVVNPLLAFT 89

  Fly    87 LIKRLHSDWETFEGSVTADSSRSNYLDTMASLKENLSFPSQDDFVGSAIALTRLQQTYQLDVAEL 151
            |||||.|||.....|:.|..:.....|....::::|  |:.:|..|:|.||.|||..|.|:|..|
Mouse    90 LIKRLQSDWRNVVHSLEATENIRALKDGYEKVEQDL--PAFEDLEGAARALMRLQDVYMLNVKGL 152

  Fly   152 ASGILNGVKYGT-----------AMSWQDCFVLG---------QHLYALRDYNHTVPWLQQSMQL 196
            |.|:...|...:           :::..|||.:|         |..|...||.|.:|||::::.|
Mouse   153 ARGVFQRVTGSSITDLYSPRQLFSLTADDCFQVGKPSCGSRSLQVAYDTGDYYHAIPWLEEAVSL 217

  Fly   197 L----GEQSYGSESASLDFMEAVVEYHREMGAHESALSLVNHVLSIEPDQRSHLLEARQQL--EE 255
            .    ||.....|::..|.::.:.....::|....||||....|...||.:.   .||..|  |.
Mouse   218 FRRAHGEWKTEDEASLEDALDYLAFACFQVGNVSCALSLSREFLVYSPDNKR---MARNVLKYER 279

  Fly   256 LITDGDKNGLLHLTARRPGDYH-ESREFRMYEQVCRGELAPLPSKQR--NLRCRLRKSRLGY--- 314
            |:.:...........:||...| ::|:  .||.:|: .|...|:..:  :|.|....:...|
Mouse   280 LLAENGHQMAAETAIQRPNVPHLQTRD--TYEGLCQ-TLGSQPTHYQIPSLYCSYETNSSPYLLL 341

  Fly   315 APFKLEELHLDPLVVQLHQVIGSKDSDSLQKTARPRIKRSTVYSLGGNGGSTAAAFRTSQGASFN 379
            .|.:.|.:||.||:...|..:..:::..:::.|.|.::||.|.|   ........:|.|:.|...
Mouse   342 QPARKEVVHLRPLIALYHDFVSDEEAQKIRELAEPWLQRSVVAS---GEKQLQVEYRISKSAWLK 403

  Fly   380 YSRNAATKLLSRHVGDFSGLNMD--YAEDLQVANYGIGGHYEPHWD--SFPENHIYQEGDLHGNR 440
            .:.:.....|...:...:||::.  |||.|||.|||||||||||:|  :.|.:.:|:...  |||
Mouse   404 DTVDPMLVTLDHRIAALTGLDIQPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYRMKS--GNR 466

  Fly   441 MATGIYYLADVEAGGGTAFPFLPLLVTPERGSLLFWYNLHPSGDQDFRTKHAACPVLQGSKWIAN 505
            :||.:.||:.|||||.|||.:....|...:.:.|||:|||.||:.|..|.||.||||.|.||:||
Mouse   467 VATFMIYLSSVEAGGATAFIYGNFSVPVVKNAALFWWNLHRSGEGDGDTLHAGCPVLVGDKWVAN 531

  Fly   506 VWIRERNQDNVRPC 519
            .||.|..|:..|||
Mouse   532 KWIHEYGQEFRRPC 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaMP	NP_524594.2	P4Ha_N	24..156	CDD:285528	40/131 (31%)
		P4Hc	336..509	CDD:214780	70/176 (40%)
P4ha3	XP_006508007.1	P4Ha_N	31..157	CDD:369820	40/131 (31%)
		P4Hc	363..535	CDD:214780	70/176 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839350
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52324
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750