DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaMP and phy-4

DIOPT Version :9

Sequence 1:	NP_524594.2	Gene:	PH4alphaMP / 43624	FlyBaseID:	FBgn0026190	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_001123049.1	Gene:	phy-4 / 189869	WormBaseID:	WBGene00012815	Length:	282	Species:	Caenorhabditis elegans

Alignment Length:	261	Identity:	73/261 - (27%)
Similarity:	126/261 - (48%)	Gaps:	20/261 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   278 ESREF--RMYEQVCRGELAPLPSKQRNLRC-RLRKSRLGYAPFKLEELHLDPLVVQLHQVIGSKD 339
            |:.||  ::::: |..||....|:...|.| ||.|..|   ..|:|.|..:|.::|.|..:..:
Worm    24 ETLEFNDKIWDK-CGKELRGDSSRDGRLVCYRLHKHLL---IRKVEILSSEPFILQYHNQVHRR- 83

  Fly   340 SDSLQKTARPRIKRSTVYSLGGNGGSTA---AAFRTSQGA-SFNYSRNAATKLLSRHVGDFSGLN 400
               |.|.|....:...:..|..:|.:|.   :..|.:.|. ..:..|.:..::......:.:.|:
Worm    84 ---LAKRAVQEAEALRLEQLKISGFTTTPEKSQVRAANGTWLIHTGRPSFARIFEGLQANINSLD 145

  Fly   401 MDYAEDLQVANYGIGGHYEPHWDSF-PENHI-YQEGDLHGNRMATGIYYLADVEAGGGTAFPFLP 463
            :..||..|:.:|...|:|.||:|.. |..:: ..||  .|||:||.:..|...:.||.|.||.|.
Worm   146 LSTAEPWQILSYNADGYYAPHYDYLNPATNVQLVEG--RGNRIATVLVILQIAKKGGTTVFPRLN 208

  Fly   464 LLVTPERGSLLFWYNLHPSGDQDFRTKHAACPVLQGSKWIANVWIRER-NQDNVRPCDLERGQEI 527
            |.:.|:.|.::.|.|...:|:.:.:|.|||||:.:|:|..|.:|:.|: ...|.:...|.|...:
Worm   209 LNIRPKAGDVIVWLNTLSTGESNSQTLHAACPIHEGTKIGATLWVHEKIFSQNTKSTGLSRQNSL 273

  Fly   528 S 528
            :
Worm   274 A 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaMP	NP_524594.2	P4Ha_N	24..156	CDD:285528
PH4alphaMP	NP_524594.2	P4Hc	336..509	CDD:214780	50/178 (28%)
phy-4	NP_001123049.1	P4Hc	81..254	CDD:214780	50/178 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910