Protein Alignment PH4alphaMP and phy-2

DIOPT Version :9

• Sequence 1: NP_524594.2
• Gene: PH4alphaMP / 43624
• FlyBaseID: FBgn0026190
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_502317.1
• Gene: phy-2 / 178170
• WormBaseID: WBGene00004025
• Length: 539
• Species: Caenorhabditis elegans
• Alignment Length: 548
• Identity: 178/548 - (32%)
• Similarity: 294/548 - (53%)
• Gaps: 42/548 - (7%)

  Fly     5 KCVLFLVLQVLSCHGEFFSSTSGLAKLFETEVVLLAELQNYVNEINQHAEALQSEIDAIR----- 64
            :.||.:.|.....|.:.|::.:.|..:...|       ::....|:|:.||.::.:|.:|
 Worm     2 RAVLLVCLLAGLAHADLFTAIADLQHMLGAE-------KDVTTIIDQYIEAERARLDDLRRYAHE 59

  Fly    65 VEHLNA-ADGI-DDYLNNPVNAFRLIKRLHSDWETFEGSVTADSSRSNYLDTMAS--LKENLSFP 125
            ..|.|| |:.: .:::.||:||:.|||||.::|:..| ::..::..|.:|..:..  ::..:.||
 Worm    60 YVHRNAHAESVGPEFVTNPINAYLLIKRLTTEWKKVE-NIMLNNKASTFLKNITDNRVRSEVKFP 123

  Fly   126 SQDDFVGSAIALTRLQQTYQLDVAELASGILNGVKYGTAMSWQDCFVLGQHLYALRDYNHTVPWL 190
            .::|..|:|.||.|||.||.||..:|::||:.|.|....:|..|.|.:|:..|..:||.|.:.|:
 Worm   124 GEEDLSGAATALLRLQDTYSLDTLDLSNGIIGGEKVSNKLSGHDTFEVGRSAYNQKDYYHCLMWM 188

  Fly   191 QQSMQLLGEQSYGSESASLDFMEAVVEYHR----EMGAHESALSLVNHVLSIEPDQRSHLLEARQ 251
            |.::..:..::    ..:::..| ::||..    :.|....||||...:..|.|:..    .|:.
 Worm   189 QVALVKIENEN----PPTIEEWE-ILEYLAYSLYQQGNVRRALSLTKRLAKIAPNHP----RAKG 244

  Fly   252 QL---EELITDGDKNGLLHLTARRPGDYHESREFRMYEQVCRGELAPLPSKQRN-LRCRLRKSR- 311
            .:   |:::...|..|.|.....:..:|....|...||.:||||:.|:..|.:| |||.|::.:
 Worm   245 NVKWYEDMLQGKDMVGDLPPIVNKRVEYDGIVERDAYEALCRGEIPPVEPKWKNKLRCYLKRDKP 309

  Fly   312 -LGYAPFKLEELHLDPLVVQLHQVIGSKDSDSLQKTARPRIKRSTVYSLGGNGGSTAAAFRTSQG 375
             |..||.|:|.|..|||.|....||...:.:.:::.|.|::||:||.: ...|....|.:|.|:.
 Worm   310 FLKLAPIKVEILRFDPLAVLFKNVIHDSEIEVIKELASPKLKRATVQN-SKTGELEHATYRISKS 373

  Fly   376 ASFNYSRNAATKLLSRHVGDFSGLNMDYAEDLQVANYGIGGHYEPHWD--SFPENHIYQEGDLHG 438
            |......:.....::|.:.||:.||...:|:|||||||:||||:||:|  ...|.:.::..:. |
 Worm   374 AWLKGDLDPVIDRVNRRIEDFTNLNQATSEELQVANYGLGGHYDPHFDFARKEEKNAFKTLNT-G 437

  Fly   439 NRMATGIYYLADVEAGGGTAFPFLPLLVTPERGSLLFWYNLHPSGDQDFRTKHAACPVLQGSKWI 503
            ||:||.::|::..|.||.|.|..|...|.|.:...||||||...|:.|.||:|||||||.|.||:
 Worm   438 NRIATVLFYMSQPERGGATVFNHLGTAVFPSKNDALFWYNLRRDGEGDLRTRHAACPVLLGVKWV 502

  Fly   504 ANVWIRERNQDNVRPCDLERGQEISLHY 531
            :|.||.|:.|:..|||.||  :|:..::
 Worm   503 SNKWIHEKGQEFTRPCGLE--EEVQENF 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaMP	NP_524594.2	P4Ha_N	24..156	CDD:285528	41/140 (29%)
		P4Hc	336..509	CDD:214780	68/174 (39%)
phy-2	NP_502317.1	P4Ha_N	21..154	CDD:285528	41/140 (29%)
		TPR_16	169..240	CDD:290168	18/75 (24%)
		P4Hc	335..508	CDD:214780	68/174 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52324
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.930