Protein Alignment PH4alphaMP and dpy-18

DIOPT Version :9

• Sequence 1: NP_524594.2
• Gene: PH4alphaMP / 43624
• FlyBaseID: FBgn0026190
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_499464.1
• Gene: dpy-18 / 176569
• WormBaseID: WBGene00001077
• Length: 559
• Species: Caenorhabditis elegans
• Alignment Length: 547
• Identity: 175/547 - (31%)
• Similarity: 275/547 - (50%)
• Gaps: 59/547 - (10%)

  Fly    10 LVLQVLSCHG----EFFSSTSGLAKLFETEVVLLAELQNYVNEINQHAEALQ------SEIDAIR 64
            |.|.||:..|    :.|:|.:.:..|.|||..:...|..|:::..:....|:      |:.:.|.
 Worm     3 LALLVLATIGYAVADLFTSIADMQNLLETERNIPKILDKYIHDEEERLVQLKKLSEEYSKKNEIS 67

  Fly    65 VEHLNAADGIDDYLNNPVNAFRLIKRLHSDWETFEGSVTADSSRSNYLDTMASLKENLSFPSQDD 129
            :|     :|:.| :.||:|||.||||...||:..|..:.|:.: .|.:.::......:.:|:.||
 Worm    68 IE-----NGLKD-ITNPINAFLLIKRKIFDWKEIESKMNANKA-GNVVSSITDDSYGVRYPTADD 125

  Fly   130 FVGSAIALTRLQQTYQLDVAELASGILNGVKYGTAMSWQDCFVLGQHLYALRDYNHTVPWLQQSM 194
            ..|:||.|.|||.||:||..:||.|.:...:.....|.:|||.:.:..|...|:.|||.|::::.
 Worm   126 LSGAAIGLLRLQDTYRLDTKDLADGKIYADQGNYTFSAKDCFEIARAAYNEHDFYHTVMWMEEAQ 190

  Fly   195 QLLGEQSYGSESASLDFME--AVVEYHREMGAHESALSLVNHVLSIEPDQRSH------------ 245
            :.||::...:.... |.:|  |...|.:....|  ||.|...:..:.|   :|
 Worm   191 RRLGDEVEPTVEVE-DILEYLAFALYKQNNLKH--ALKLTEELYKMNP---THPRAKGNVKWYED 249

  Fly   246 LLEARQQLEELITDGD-KNGLLHLTARRPGDYHESREFRMYEQVCRGELAPLPSKQ-RNLRCRLR 308
            |||     :|.:...| :..|..:..|||.....:.|..|||.:||.|: |:..|. ..|.|..:
 Worm   250 LLE-----QEGVRRSDMRKNLPPIQNRRPDSVLGNTERTMYEALCRNEV-PVSQKDISRLYCYYK 308

  Fly   309 KSR--LGYAPFKLEELHLDPLVVQLHQVIGSKDSDSLQKTARPRIKRSTVYSLGGNGGSTAAAFR 371
            :.|  |.|||.|:|....:||.|....||...:..::|:.|:|::.|:||:. ...|....|.:|
 Worm   309 RDRPFLVYAPIKVEIKRFNPLAVLFKDVISDDEVAAIQELAKPKLARATVHD-SVTGKLVTATYR 372

  Fly   372 TSQGASFNYSRNAATKLLSRHVGDFSGLNMDYAEDLQVANYGIGGHYEPHWDSFPENHIYQEGDL 436
            .|:.|..........:.:::.:|..:.|.|:.||:||:|||||||||:||:|     |..:|...
 Worm   373 ISKSAWLKEWEGDVVETVNKRIGYMTNLEMETAEELQIANYGIGGHYDPHFD-----HAKKEESK 432

  Fly   437 H------GNRMATGIYYLADVEAGGGTAFPFLPLLVTPERGSLLFWYNLHPSGDQDFRTKHAACP 495
            .      |||:||.::|::....||||.|......:.|.:...||||||:..||.:..|:|||||
 Worm   433 SFESLGTGNRIATVLFYMSQPSHGGGTVFTEAKSTILPTKNDALFWYNLYKQGDGNPDTRHAACP 497

  Fly   496 VLQGSKWIANVWIRERNQDNVRPCDLE 522
            ||.|.||::|.||.|:..:..|||.|:
 Worm   498 VLVGIKWVSNKWIHEKGNEFRRPCGLK 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaMP	NP_524594.2	P4Ha_N	24..156	CDD:285528	44/137 (32%)
		P4Hc	336..509	CDD:214780	65/178 (37%)
dpy-18	NP_499464.1	P4Ha_N	21..152	CDD:285528	44/137 (32%)
		P4Hc	338..511	CDD:214780	65/178 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52324
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.930