Protein Alignment PH4alphaMP and p4ha3

DIOPT Version :9

• Sequence 1: NP_524594.2
• Gene: PH4alphaMP / 43624
• FlyBaseID: FBgn0026190
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_031752143.1
• Gene: p4ha3 / 100495824
• XenbaseID: XB-GENE-962355
• Length: 547
• Species: Xenopus tropicalis
• Alignment Length: 556
• Identity: 173/556 - (31%)
• Similarity: 266/556 - (47%)
• Gaps: 68/556 - (12%)

  Fly     3 LAKCVLFLVLQVLSCHGEFFSSTSGLAKLFETEVVLLAELQNYVNEINQHAEALQSEIDAIRVEH 67
            |..||.:  |..|....:.:||.:.:.:....|..||..|..|:.:..|....|:...:.::..|
 Frog    15 LLLCVSW--LHWLHAGADMYSSMASIQQAVGMEGALLQHLGQYLQQETQRLSDLRRFYEKVQASH 77

  Fly    68 LNAADGIDDYLNNPVNAFRLIKRLHSDWETFEGSVTADSSRSNYLDTMASLKENL-----SFPSQ 127
            ......:.|    |:.|:.|:|||.|:|..     ...||.:|  :.:.:|||..     ..|:.
 Frog    78 QAGGPPVQD----PILAYTLLKRLQSEWMN-----VVHSSEAN--ENIQALKEGYEKVKQDLPAP 131

  Fly   128 DDFVGSAIALTRLQQTYQLDVAELASG-----------ILNGVKYGTAMSWQDCFVLGQHLYALR 181
            :|..|:|.||.|||..|.|:|..||.|           :|....:.:.||..|||.:|:..|.:.
 Frog   132 EDVEGAAKALMRLQDVYSLNVNGLARGMFQRSSSSDTKLLYNPPHLSIMSADDCFHIGKVAYDME 196

  Fly   182 DYNHTVPWLQQSMQLLGEQSYGS----ESASLDFMEAVVEY----HREMGAHESALSLVNHVLSI 238
            ||.|::|||::::... ..|||:    :..||   |..::|    :.:.|....||.|....|..
 Frog   197 DYYHSIPWLEEAVSRF-RGSYGNWRTEDEGSL---EEALDYLAFSYYKAGNISHALDLSRECLLY 257

  Fly   239 EPDQ---RSHLLEARQQLEELIT-DGDKNGLLHLTARRPGDYH-ESREFRMYEQVCR--GELAPL 296
            :||.   ..::.:..|.|.|..| |.|..   .:..:||...| ::|:  :||.:|:  |. .|.
 Frog   258 DPDNGRLARNIAKYEQILYESPTADADAE---EMKLQRPNVTHLKTRD--LYEGLCQTLGS-QPT 316

  Fly   297 PSKQRNLRCRLRKSRLGY---APFKLEELHLDPLVVQLHQVIGSKDSDSLQKTARPRIKRSTVYS 358
            ..:..::.|....:...|   .|.|.|.:.|.|.||..|..:...:::.:::.|.|.:.||.|.|
 Frog   317 SYEDPHMSCMYDTNSHPYLLLQPMKKEIVSLRPQVVLYHDFVSDLEAEKIKELASPWLHRSVVAS 381

  Fly   359 LGGNGGSTA-AAFRTSQGASFNYSRNAATKLLSRHVGDFSGLNM--DYAEDLQVANYGIGGHYEP 420
                |...| |.:|.|:.|....:.:...:.|...:...:|||.  .|||.|||.||||||||||
 Frog   382 ----GEKQAEAEYRISKSAWLKDTIHPFVQNLDTRISAVTGLNAHPPYAEYLQVVNYGIGGHYEP 442

  Fly   421 HWD--SFPENHIYQEGDLHGNRMATGIYYLADVEAGGGTAFPFLPLLVTPERGSLLFWYNLHPSG 483
            |:|  :..::.:|:...  |||:||.:.||:.|:.||.|||.|........:.:.:||:|||.:|
 Frog   443 HFDHATSRKSPLYRTNT--GNRLATFMIYLSHVDLGGSTAFVFANFSSPVVKNAAVFWWNLHRNG 505

  Fly   484 DQDFRTKHAACPVLQGSKWIANVWIRERNQDNVRPC 519
            ..|..|.||.|||:.||||:||.||.|..|:..|||
 Frog   506 LGDEDTLHAGCPVIIGSKWVANKWIHEFGQEFHRPC 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaMP	NP_524594.2	P4Ha_N	24..156	CDD:285528	39/147 (27%)
		P4Hc	336..509	CDD:214780	69/177 (39%)
p4ha3	XP_031752143.1	P4Ha_N	35..>104	CDD:400573	17/77 (22%)
		TPR repeat	182..210	CDD:276809	11/27 (41%)
		TPR repeat	215..257	CDD:276809	12/44 (27%)
		P4Hc	359..531	CDD:214780	69/177 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	64	1.000	Domainoid score	I9960
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.000