Protein Alignment PH4alphaMP and p4ha1b

DIOPT Version :9

• Sequence 1: NP_524594.2
• Gene: PH4alphaMP / 43624
• FlyBaseID: FBgn0026190
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_999856.1
• Gene: p4ha1b / 100003675
• ZFINID: ZDB-GENE-030131-4089
• Length: 536
• Species: Danio rerio
• Alignment Length: 544
• Identity: 187/544 - (34%)
• Similarity: 304/544 - (55%)
• Gaps: 35/544 - (6%)

  Fly     1 MLLAKCVLFLVLQVLSCHGEFFSSTSGLAKLFETEVVLLAELQNYVNEINQHAEALQSEIDAIRV 65
            |:||..:|..:...|..|.:||:||..:..|...|..|:..|:.|:.:.....|.::...|.:..
Zfish     1 MMLAWFLLSFLFHFLYAHNDFFTSTGQMTDLLYAEKDLVTSLKEYIKQEENRLEQVKEWADKLDS 65

  Fly    66 EHLNAADGIDDYLNNPVNAFRLIKRLHSDWETFEGSVTADSSRSNYLDTMASLKENLSFPSQDDF 130
            ..:.|....:.:|.:|||||:|:|||:|:|...|..|..|:: :.::..:...::  .||:.:|.
Zfish    66 LTITATQDPEGFLGHPVNAFKLMKRLNSEWSDLENLVLKDTT-NGFISNLTVQRQ--YFPTDEDQ 127

  Fly   131 VGSAIALTRLQQTYQLDVAELASGILNGVKYGTAMSWQDCFVLGQHLYALRDYNHTVPWLQQSMQ 195
            .|:|.||.|||.||||....::||.|.||.:.:.|:.:||:.||:..|:..||.||..|:.|::.
Zfish   128 TGAAKALLRLQDTYQLSANAISSGDLPGVVHKSRMTVEDCYELGKIAYSDADYYHTELWMAQALS 192

  Fly   196 LL--GEQSYGSESASLDFMEAVVEYHREMGAHESALSLVNHVLSIEPDQR---------SHLLEA 249
            .|  ||:|...:...:|::...:   .:.|..:.||.|...:|.::|:..         ...||.
Zfish   193 QLDEGEESPIDKVTVMDYLSYAI---YQQGELDRALELTKRMLKLDPNHHRANGNLKYFEFQLEK 254

  Fly   250 RQQLEELITDGDKNGLLHLTARRPGDYHESR----EFRMYEQVCRGELAPL-PSKQRNLRCRL-- 307
            :::.|....:.|:..:|.   :|......|:    |.:.||::||||...| |.:|..|.||.
Zfish   255 QRKAENEKKEEDQKRVLD---KRDAQRKRSKDPLPERKKYERLCRGEGIKLTPRRQSRLFCRYSN 316

  Fly   308 --RKSRLGYAPFKLEELHLDPLVVQLHQVIGSKDSDSLQKTARPRIKRSTVYSLGGNGGSTAAAF 370
              |..||..||.|.|:....|.:|:.|::|...:.:::::.|:||::|:|: |....|....|.:
Zfish   317 NNRNPRLLLAPVKQEDEWDRPRIVRYHEIISDSEIETVKEMAKPRLRRATI-SNPITGVLETAPY 380

  Fly   371 RTSQGASFNYSRNAATKLLSRHVGDFSGLNMDYAEDLQVANYGIGGHYEPHWD--SFPENHIYQE 433
            |.|:.|..:...::..:.:::.:.|.:||.||.||:|||||||:||.||||:|  ...|...::|
Zfish   381 RISKSAWLSGYEHSTIERINQRIEDVTGLEMDTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKE 445

  Fly   434 -GDLHGNRMATGIYYLADVEAGGGTAFPFLPLLVTPERGSLLFWYNLHPSGDQDFRTKHAACPVL 497
             |.  |||:||.::|::||.|||.|.|..:...|.|::|:.:|||||.|||:.|:.|:|||||||
Zfish   446 LGT--GNRIATWLFYMSDVSAGGATVFTDVGAAVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVL 508

  Fly   498 QGSKWIANVWIRERNQDNVRPCDL 521
            .|:||::|.||.||.|:..|||.|
Zfish   509 VGNKWVSNKWIHERGQEFRRPCAL 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaMP	NP_524594.2	P4Ha_N	24..156	CDD:285528	41/131 (31%)
		P4Hc	336..509	CDD:214780	73/175 (42%)
p4ha1b	NP_999856.1	P4Ha_N	24..153	CDD:285528	41/131 (31%)
		TPR repeat	164..199	CDD:276809	13/34 (38%)
		TPR_16	168..238	CDD:290168	20/72 (28%)
		TPR repeat	204..234	CDD:276809	6/32 (19%)
		P4Hc	347..520	CDD:214780	73/175 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52324
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.930