DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaSG2 and P4H5

DIOPT Version :9

Sequence 1:	NP_651801.1	Gene:	PH4alphaSG2 / 43623	FlyBaseID:	FBgn0039779	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_179363.1	Gene:	P4H5 / 816281	AraportID:	AT2G17720	Length:	291	Species:	Arabidopsis thaliana

Alignment Length:	271	Identity:	81/271 - (29%)
Similarity:	120/271 - (44%)	Gaps:	50/271 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   265 VPGKNVQETKPSWFSNYTRLCQGRRLPEERSGDPLRCYLDGKRHAYFTLAPLQVEPVHLDPDINV 329
            :|..|...:|.:..:|..|..:.....||.:|:                  ..||.:..:|...|
plant    45 LPNANRNSSKTNDLTNIVRKSETSSGDEEGNGE------------------RWVEVISWEPRAVV 91

  Fly   330 YHGMLSSKQILSIFEEADKEEMVRSAVAG--SGGEGTVRDLRVSQQTWLDY-KSPVMNSVGRIIQ 391
            ||..|::::...:...| |..||:|.|..  :||....| :|.|..|:|.. ...|:..:.:.|.
plant    92 YHNFLTNEECEHLISLA-KPSMVKSTVVDEKTGGSKDSR-VRTSSGTFLRRGHDEVVEVIEKRIS 154

  Fly   392 FVSGFDMAGAEHMQVANYGVGGQYEPHPDYF--EVNLPKNFEGDRISTSMFYLSDVEQGGYTVF- 453
            ..:...:...|.:||.:|.||.:||||.|||  |.| .|| .|.||:|.:.|||||:.||.|||
plant   155 DFTFIPVENGEGLQVLHYQVGQKYEPHYDYFLDEFN-TKN-GGQRIATVLMYLSDVDDGGETVFP 217

  Fly   454 -TKLNV------------------FLPPVKGALVMWHNLHRSLHVDARTLHAGCPVIVGSKRIGN 499
             .:.|:                  .||..:.||:.| |:.....:|..:||.||||:.|:|....
plant   218 AARGNISAVPWWNELSKCGKEGLSVLPKKRDALLFW-NMRPDASLDPSSLHGGCPVVKGNKWSST 281

  Fly   500 IWMHSGYQEFR 510
            .|.|  ..||:
plant   282 KWFH--VHEFK 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG2	NP_651801.1	P4Ha_N	28..163	CDD:285528
PH4alphaSG2	NP_651801.1	P4Hc	335..503	CDD:214780	63/192 (33%)
P4H5	NP_179363.1	PLN00052	75..290	CDD:177683	73/239 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.920