DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaSG2 and p4htma

DIOPT Version :9

Sequence 1:	NP_651801.1	Gene:	PH4alphaSG2 / 43623	FlyBaseID:	FBgn0039779	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_001074160.1	Gene:	p4htma / 791209	ZFINID:	ZDB-GENE-070112-2222	Length:	478	Species:	Danio rerio

Alignment Length:	310	Identity:	70/310 - (22%)
Similarity:	102/310 - (32%)	Gaps:	103/310 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   303 LDGKRHAYFTLAPLQVEPVHLDP-----DINVYHGMLSSKQILSIFEEAD--------------- 347
            |.|..|:.....|.|.|.:..|.     |:| ..|:|..::|||:....|
Zfish   163 LKGLTHSSLLTNPDQEEQLTQDELFSLLDLN-QDGLLQREEILSLSHSTDGSWLSSYNLRKIHTG 226

  Fly   348 ----------KEEMVR---------SAVAGSGGEGTVRDLRVSQQTWLD------YKSPVMNSVG 387
                      .:|..|         .|..|..|...||......:.:|.      .|| |.|.|.
Zfish   227 LETNPSGVLSLQEFKRVSGGVLRYSGAAQGLDGHTKVRQRSTHTRLYLGEGTHHLLKS-VRNRVT 290

  Fly   388 RIIQFVSGF-DMAGAEHMQVANYGVG-------GQYEPHPD------YFEVNLPKNFEGDRISTS 438
            |:.:..|.. |:  :|.|:|..|..|       .....|||      :...| ..|....|..|.
Zfish   291 RLTRLPSSLVDL--SEAMEVVRYEQGVFSHAHHDSSPTHPDNSCTHTHLAAN-TSNQVACRYLTV 352

  Fly   439 MFYLSDVEQGGYTVF---------------------TKLNVFLPPVKGALVMWHNLHRS------ 476
            :.||:..:.||.|.|                     .|.|:.:.||.|..::|:| |.|
Zfish   353 LLYLNSADSGGETSFPVADNRTYEEEVLGDLSQQYCDKGNLKVKPVAGTALLWYN-HLSDGNGWV 416

  Fly   477 LHVDARTLHAGCPVIVGSKRIGNIWMHSGYQEFRRPCNLTSDSYKSLAYR 526
            ..:|..:||..|.|..|.|..|::|:           |:..|..:...|:
Zfish   417 GELDEFSLHGDCLVTRGFKWTGSVWV-----------NIDPDQQRQERYQ 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG2	NP_651801.1	P4Ha_N	28..163	CDD:285528
PH4alphaSG2	NP_651801.1	P4Hc	335..503	CDD:214780	56/248 (23%)
p4htma	NP_001074160.1	2OG-FeII_Oxy	<272..442	CDD:304390	44/174 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583478
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740