DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaSG2 and Y43F8B.19

DIOPT Version :9

Sequence 1:	NP_651801.1	Gene:	PH4alphaSG2 / 43623	FlyBaseID:	FBgn0039779	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_001123044.2	Gene:	Y43F8B.19 / 6418801	WormBaseID:	WBGene00077688	Length:	243	Species:	Caenorhabditis elegans

Alignment Length:	215	Identity:	56/215 - (26%)
Similarity:	89/215 - (41%)	Gaps:	15/215 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   316 LQVEPVHLDPDINVYHGMLSSKQI---LSIFEEADKEEMVRSAVAGSGGEGTVRDLRVSQQTWLD 377
            ::||.|...|.:.:|..:.:.||:   |.:.|....||.:   |....|...|..:|.:..|.:.
Worm    22 VKVEVVAWRPGLVIYRDLFTGKQVRDHLELMEHLKFEEQL---VVNDDGNDIVSKIRRANGTQVF 83

  Fly   378 YKS-PVMNSVGRIIQ-FVSGFDMAGAEHMQVANYGVGGQYEPHPDYFEVNLPKNFE------GDR 434
            ::. |...|:....: .:...:...||.:...:|..||.|..|.||......|.::      |:|
Worm    84 HEDHPAARSIWDTAKNLLPNLNFKTAEDILALSYNPGGHYAAHHDYLLYPSEKEWDEWMRVNGNR 148

  Fly   435 ISTSMFYLSDVEQGGYTVFTKLNVFLPPVKGALVMWHNLHRSLHVDARTLHAGCPVIVGSKRIGN 499
            ..|.:......|.||.|||.:|...:....|....|.|...:...:..:.|||||:..|.|:|..
Worm   149 FGTLIMAFGAAESGGATVFPRLGAAVRTKPGDAFFWFNAMGNSEQEDLSEHAGCPIYKGQKQIST 213

  Fly   500 IWMHSGYQEFRRPCNLTSDS 519
            ||:....|..... .|:|||
Worm   214 IWLRMRDQPILEQ-TLSSDS 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG2	NP_651801.1	P4Ha_N	28..163	CDD:285528
PH4alphaSG2	NP_651801.1	P4Hc	335..503	CDD:214780	46/178 (26%)
Y43F8B.19	NP_001123044.2	P4Hc	43..217	CDD:214780	46/176 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810