Protein Alignment PH4alphaSG2 and PH4alphaNE1

DIOPT Version :9

• Sequence 1: NP_651801.1
• Gene: PH4alphaSG2 / 43623
• FlyBaseID: FBgn0039779
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_733374.1
• Gene: PH4alphaNE1 / 43625
• FlyBaseID: FBgn0039780
• Length: 537
• Species: Drosophila melanogaster
• Alignment Length: 553
• Identity: 193/553 - (34%)
• Similarity: 289/553 - (52%)
• Gaps: 59/553 - (10%)

  Fly     7 LYIGIFQLIIWVGVANGEFYSSVDSMQDLAQVEEELLNATRSYVESQQKQLDFYRRYVEQIKREH 71
            |.:|:..|:....:|: :::||:..::||...|:.|....||.|.:.|..|......:..|::||
  Fly     6 LLVGLIFLLAQGSLAS-DYFSSITGLEDLLHTEQYLTRELRSKVNAIQTALQQLESELSSIEKEH 69

  Fly    72 EWATSQLKLDDYLGHPLHAFRLIKRLVRDWD------SLIFEPILANNAREEFRAFVEVLSRDLG 130
            ..|.|.  .::||.:|::.:||:|||..||.      .|:.|.:..|..||          ..|.
  Fly    70 TMAASD--TENYLTNPVNVYRLMKRLHTDWSLMEGRVQLMAEEMNFNATRE----------YGLS 122

  Fly   131 YPDQSELQGAIKGLARLQKVYNLATSDLADGIIGGLNYGSDLRWRECYEIGVQLFDLGEYQRSLE 195
            ||.|.:::||...|.|||..|.|..:.:|.||:.|:.||||:.|::|:|:|.|||::.:|..:..
  Fly   123 YPSQEDVEGAALALVRLQSTYKLDVAQVAQGILNGVKYGSDMSWQDCFELGQQLFEMEDYNNTKV 187

  Fly   196 WLQVAFILLRNSPREEKDADHYLS----------DIREYASMANFELGNPKKAARLLSQILESQP 250
            ||:.:...||   |:...|..:|:          :..|..:.:.|:||:...|..|..::|:..|
  Fly   188 WLRESMERLR---RQTSHAPSHLAPTSGPDTVTLNKMEATAKSLFQLGDFDTAFELSQRVLQFDP 249

  Fly   251 T-----HSAQQ--------TQKYLESRVPGKNVQETKPSWFSNYTRLCQGRRLPEERSGDPLRCY 302
            .     |...:        ...||.......::.:.    |:.|.::|:|...|..|  ..|||.
  Fly   250 KRIRNWHLGDKGTAPPEDIDDVYLPKHSDSYSLSQE----FAKYEKVCRGEVHPIVR--QELRCR 308

  Fly   303 LDGKRHAYFTLAPLQVEPVHLDPDINVYHGMLSSKQILSIFEEADKEEMVRSAVAG-SGGEGTVR 366
            .....|.|..||||::|...|||.:..:|.:||..:|..:.|.| ...|.||.|.. .||:....
  Fly   309 YSRGNHPYRFLAPLKLEEHSLDPYVATFHDILSPGKISQLREMA-VPRMHRSTVNPLPGGQLKKS 372

  Fly   367 DLRVSQQTWLDYKS-PVMNSVGRIIQFVSGFDMAGAEHMQVANYGVGGQYEPHPDYFEVNLPKNF 430
            ..|||:..||.|:| |.|..:.|.::..:|.|....|.:|||||||||.||||.|:|..  |.::
  Fly   373 AFRVSKNAWLAYESHPTMVGMLRDLKDATGLDTTFCEQLQVANYGVGGHYEPHWDFFRD--PNHY 435

  Fly   431 ---EGDRISTSMFYLSDVEQGGYTVFTKLNVFLPPVKGALVMWHNLHRSLHVDARTLHAGCPVIV 492
               ||:||:|::||||:|||||.|.|..|::.:.|..|.::.|:||||||..|.||.||||||:.
  Fly   436 PAEEGNRIATAIFYLSEVEQGGATAFPFLDIAVKPQLGNVLFWYNLHRSLDKDYRTKHAGCPVLK 500

  Fly   493 GSKRIGNIWMHSGYQEFRRPCNLTSDSYKSLAY 525
            |||.|||:|:|...|.|.|||::..|...||.|
  Fly   501 GSKWIGNVWIHEVTQTFARPCDVFRDHEVSLEY 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG2	NP_651801.1	P4Ha_N	28..163	CDD:285528	44/140 (31%)
		P4Hc	335..503	CDD:214780	81/172 (47%)
PH4alphaNE1	NP_733374.1	P4Ha_N	26..155	CDD:285528	44/140 (31%)
		P4Hc	341..511	CDD:214780	81/172 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461745
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	10	9.900