Protein Alignment PH4alphaSG2 and PH4alphaEFB

DIOPT Version :9

• Sequence 1: NP_651801.1
• Gene: PH4alphaSG2 / 43623
• FlyBaseID: FBgn0039779
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_733371.1
• Gene: PH4alphaEFB / 43620
• FlyBaseID: FBgn0039776
• Length: 550
• Species: Drosophila melanogaster
• Alignment Length: 554
• Identity: 179/554 - (32%)
• Similarity: 280/554 - (50%)
• Gaps: 54/554 - (9%)

  Fly     4 RHCLYIGIFQLIIWVGVANGEFYSSVDSMQDLAQVEEELLNATRSYVESQQKQLDFYRRYVEQIK 68
            |..|.:||  |::..|.||||.|:::..|::|.:.|..|:.....|:..|:.:|:|.:..:::.:
  Fly     6 RLMLLLGI--LLLVGGPANGEVYTALAEMEELLETESVLITNLEGYIRVQEDKLNFLKNKMDEYQ 68

  Fly    69 REHEWATSQLKLDDYLGHPLHAFRLIKRLVRDWDSLIFEPILANNAREEFRAFVEVLSRDLGYPD 133
            |||..|:..:..  |:.:|::|:.|.|||..||..:  |.::.::...:|...:......|.:|.
  Fly    69 REHSDASHDITA--YVSNPINAYLLTKRLTTDWRQV--ENLMEHDVGTDFLQNITQYRSLLKFPS 129

  Fly   134 QSELQGAIKGLARLQKVYNLATSDLADGIIGGLNYGSDLRWRECYEIGVQLFDLGEYQRSLEWLQ 198
            ..:|.||...|.|||..|.|.||.:|.|.:.|:.|.:::...:|:|:|.|.:...:|..::.|:.
  Fly   130 DEDLNGAAVALLRLQDTYQLDTSSVARGKLNGIQYSTEMSSDDCFELGRQSYVNHDYYHTVLWMN 194

  Fly   199 VAFILLRNSPREEKDADHYLS----DIREYASMANFELGNPKKAARLLSQILESQPTHS------ 253
            .|...:...|     .:|..|    ||.||.:.:.::.||.:.|..:.:::|:..|.|.
  Fly   195 EAMARMLEEP-----TNHTQSFTKADILEYLAFSTYKEGNIESALTMTNELLQLLPHHERANGNK 254

  Fly   254 -------AQQ-----------TQKYLESRVPGKNVQETKPSWFS-----NYTRLCQGRRLPEERS 295
                   |||           |.:..:|.:|   |.::.|:.|.     .|..||:|...|....
  Fly   255 RFYEKEIAQQLQLRKMKGDDGTDEMPKSDLP---VAKSDPAIFDMTERRAYEMLCRGELKPSPSD 316

  Fly   296 GDPLRCYLDGKRHAYFTLAPLQVEPVHLDPDINVYHGMLSSKQILSIFEEADKEEMVRSAVAGS- 359
            ...|||.....|..:..|.||::|.||.||.|.:||..:...:| .:.:...:....|:.|..|
  Fly   317 LRSLRCRYVTNRVPFLRLGPLKLEEVHADPYIVIYHDAMYDSEI-DLIKRMARPRFRRATVQNSV 380

  Fly   360 GGEGTVRDLRVSQQTWL-DYKSPVMNSVGRIIQFVSGFDMAGAEHMQVANYGVGGQYEPHPDYFE 423
            .|.....:.|:|:..|| ..:..|:.:|.:....::|.||..||.:||.|||:||.||||.|:..
  Fly   381 TGALETANYRISKSAWLKTQEDRVIETVVQRTADMTGLDMDSAEELQVVNYGIGGHYEPHFDFAR 445

  Fly   424 VNLPKNFE----GDRISTSMFYLSDVEQGGYTVFTKLNVFLPPVKGALVMWHNLHRSLHVDARTL 484
            ....:.||    |:||:|.:||:|||||||.||||.|:..|.|.||....|.||||....|.||.
  Fly   446 KEEQRAFEGLNLGNRIATVLFYMSDVEQGGATVFTSLHTALFPKKGTAAFWMNLHRDGQGDVRTR 510

  Fly   485 HAGCPVIVGSKRIGNIWMHSGYQEFRRPCNLTSD 518
            ||.|||:.|:|.:.|.|:|...|||||||:|..|
  Fly   511 HAACPVLTGTKWVSNKWIHERGQEFRRPCDLEED 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG2	NP_651801.1	P4Ha_N	28..163	CDD:285528	38/134 (28%)
		P4Hc	335..503	CDD:214780	69/173 (40%)
PH4alphaEFB	NP_733371.1	P4Ha_N	28..159	CDD:285528	38/134 (28%)
		P4Hc	356..529	CDD:214780	69/173 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461746
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	10	9.900