Protein Alignment PH4alphaSG2 and p4ha2

DIOPT Version :10

• Sequence 1: NP_651801.1
• Gene: PH4alphaSG2 / 43623
• FlyBaseID: FBgn0039779
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: XP_005173949.1
• Gene: p4ha2 / 373132
• ZFINID: ZDB-GENE-030827-1
• Length: 542
• Species: Danio rerio
• Alignment Length: 531
• Identity: 166/531 - (31%)
• Similarity: 275/531 - (51%)
• Gaps: 50/531 - (9%)

  Fly    24 EFYSSVDSMQDLAQVEEELLNATRSYVESQQKQLDFYRRYVEQIKREHEWATSQLKLDDYLGHPL 88
            |.::|:..|.:|...|.||:.:.:.|:::::::|:..|.:..::.:....:||.  .:.:|.||:
Zfish    21 EIFTSIGQMTNLIFTERELVQSLKEYIQAEEQKLETVRSWANKLDKLTRTSTSD--PEGFLAHPV 83

  Fly    89 HAFRLIKRLVRDWDSLIFEPILANNAREEFRAFVEVLSRDLGYPDQSELQGAIKGLARLQKVYNL 153
            :|::|:|||..:|..|  |.::..:..:.|.:.:.|..:  .:||:.:.:||.|.|.|||..|.|
Zfish    84 NAYKLMKRLNTEWSEL--ESLVLQDPSDGFISNMSVHRQ--YFPDEEDEKGAAKALLRLQDTYKL 144

  Fly   154 ATSDLADGIIGGLNYGSDLRWR------ECYEIGVQLFDLGEYQRSLEWLQVAFILLRNSPREEK 212
            .....:.|.:.|....|.:|:.      :|:::|...::..:|..|:.|:|.:   ||.....|
Zfish   145 DAESFSKGKLPGQRQHSGVRYNALLTVDDCFDMGKMAYNDNDYYHSVLWMQQS---LRQMDSGE- 205

  Fly   213 DADHYLSDIREYASMANFELGNPKKAARLLSQILESQPTHS-AQQTQKYLESRVPGKNVQET--- 273
            :|....:|:.:|.|.:.:::|:..:|..|..::|...|:|. |....:|.| |:..|.:|::
Zfish   206 EAKTPKADVLDYLSYSVYQMGDLPRAIELTRRLLAIDPSHQRAGGNLRYFE-RLLSKELQDSGQT 269

  Fly   274 -------KPSWFSNYTR-------------LCQGR--RLPEERSGDPLRCYLDGKRHAYFTLAPL 316
                   :|.....|.|             ||:|.  ::..:|.......|.||.|:....|.|:
Zfish   270 QPEPADERPIQLDTYQRPKDYLPEREAYEALCRGEGVKMTTKRQSRLFCRYRDGNRNPRLLLKPM 334

  Fly   317 QVEPVHLDPDINVYHGMLSSKQILSIFEEADKEEMVRSAVAG-SGGEGTVRDLRVSQQTWLDYK- 379
            :.|.....|.|..:...||.::|..| :|....::.|:.|.. ..|..||...|||:..||:.:
Zfish   335 KEEDEWDSPHIVRFLEALSDEEIQKI-KEIATPKLARATVRDPKTGVLTVAHYRVSKSAWLEGED 398

  Fly   380 SPVMNSVGRIIQFVSGFDMAGAEHMQVANYGVGGQYEPHPDYFEVNLPKNFE----GDRISTSMF 440
            .||:..|.:.|:.::|..:..||.:||||||||||||||.|:...:.|..|:    |:|::|.:.
Zfish   399 DPVIARVNQRIEDITGLTVDTAELLQVANYGVGGQYEPHFDFSRKDEPDAFKSLGTGNRVATYLN 463

  Fly   441 YLSDVEQGGYTVFTKLNVFLPPVKGALVMWHNLHRSLHVDARTLHAGCPVIVGSKRIGNIWMHSG 505
            |:||||.||.|||......:.|.||..|.|:||.||...|.||.||.|||:||||.:.|.|:|..
Zfish   464 YMSDVEAGGATVFPDFGASVWPRKGTAVFWYNLFRSGEGDYRTRHAACPVLVGSKWVSNKWIHER 528

  Fly   506 YQEFRRPCNLT 516
            .|||||||.||
Zfish   529 GQEFRRPCGLT 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG2	NP_651801.1	P4Ha_N	28..165	CDD:462433	36/136 (26%)
		CpoB	<178..263	CDD:441335	20/85 (24%)
		P4Hc	335..503	CDD:214780	74/173 (43%)
p4ha2	XP_005173949.1	P4Ha_N	25..156	CDD:462433	36/136 (26%)
		NrfG	177..280	CDD:443378	25/107 (23%)
		P4Hc	353..526	CDD:214780	74/173 (43%)