Protein Alignment PH4alphaSG2 and P4ha2

DIOPT Version :10

• Sequence 1: NP_651801.1
• Gene: PH4alphaSG2 / 43623
• FlyBaseID: FBgn0039779
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_001101745.1
• Gene: P4ha2 / 360526
• RGDID: 1309673
• Length: 535
• Species: Rattus norvegicus
• Alignment Length: 540
• Identity: 172/540 - (31%)
• Similarity: 268/540 - (49%)
• Gaps: 53/540 - (9%)

  Fly    14 LIIWVGV---ANGEFYSSVDSMQDLAQVEEELLNATRSYVESQQKQLDFYRRYVEQIKREHEWAT 75
            |:.|.||   ...||::|:..|.||...|::|:.:.:.|:.:::.:|...:.:..::    |..|
  Rat     9 LMSWFGVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILAEEAKLSKIKSWASKM----EALT 69

  Fly    76 SQLKLD--DYLGHPLHAFRLIKRLVRDWDSLIFEPILANNAREEFRAFVEVLSRDLGYPDQSELQ 138
            |:...|  .||.||::|::|:|||..||.:|  ..::..:|...|.|.:.| .|.. :|...:..
  Rat    70 SKSAADPEGYLAHPVNAYKLVKRLNTDWPAL--GDLVLQDAAAGFVANLSV-QRQF-FPTDEDES 130

  Fly   139 GAIKGLARLQKVYNLATSDLADGIIGGLNYGSDLRWRECYEIGVQLFDLGEYQRSLEWLQVAFIL 203
            ||.:.|.|||..|.|....::.|.:.|..|.:.|...:|:.:|...::.|:|..::.|::.  :|
  Rat   131 GAARALMRLQDTYKLDPDMISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQ--VL 193

  Fly   204 LRNSPREEKDADHYLSDIREYASMANFELGNPKKAARLLSQILESQPTHS--------------- 253
            .:....||......|  :.:|.|.|.|:||:..:|..|..::|...|:|.
  Rat   194 KQLDAGEEATVTKSL--VLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEE 256

  Fly   254 ------AQQTQKYLESRVPGKNVQETKPSWFSN---YTRLCQGRRLP-EERSGDPLRC-YLDGKR 307
                  :.||...|.|:   :|:.|....:...   |..||:|..:. ..|....|.| |..|.|
  Rat   257 ERGKSLSNQTDAGLASQ---ENLYERPVDYLPERDVYESLCRGEGIKMTPRRQKRLFCRYHHGNR 318

  Fly   308 HAYFTLAPLQVEPVHLDPDINVYHGMLSSKQILSIFEEADKEEMVRSAVAG-SGGEGTVRDLRVS 371
            .....:||.:.|.....|.|..|:.::|.::|..| :|..|.::.|:.|.. ..|..||...|||
  Rat   319 VPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERI-KEIAKPKLARATVRDPKTGVLTVASYRVS 382

  Fly   372 QQTWLDY-KSPVMNSVGRIIQFVSGFDMAGAEHMQVANYGVGGQYEPHPDYFEVNLPKNFE---- 431
            :.:||:. ..||:..|.|.:|.::|..:..||.:||||||:|||||||.|:...:....|:
  Rat   383 KSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDERDAFKRLGT 447

  Fly   432 GDRISTSMFYLSDVEQGGYTVFTKLNVFLPPVKGALVMWHNLHRSLHVDARTLHAGCPVIVGSKR 496
            |:|::|.:.|:||||.||.|||..|...:.|.||..|.|:||.||...|.||.||.|||:||.|.
  Rat   448 GNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKW 512

  Fly   497 IGNIWMHSGYQEFRRPCNLT 516
            :.|.|.|...|||.|||..|
  Rat   513 VSNKWFHERGQEFLRPCGTT 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG2	NP_651801.1	P4Ha_N	28..165	CDD:462433	39/138 (28%)
		CpoB	<178..263	CDD:441335	22/105 (21%)
		P4Hc	335..503	CDD:214780	74/173 (43%)
P4ha2	NP_001101745.1	P4Ha_N	26..157	CDD:462433	39/138 (28%)
		P4Hc	346..519	CDD:214780	74/173 (43%)