Protein Alignment PH4alphaSG2 and PH4alphaNE3

DIOPT Version :9

• Sequence 1: NP_651801.1
• Gene: PH4alphaSG2 / 43623
• FlyBaseID: FBgn0039779
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_651814.1
• Gene: PH4alphaNE3 / 326114
• FlyBaseID: FBgn0051017
• Length: 481
• Species: Drosophila melanogaster
• Alignment Length: 508
• Identity: 130/508 - (25%)
• Similarity: 240/508 - (47%)
• Gaps: 73/508 - (14%)

  Fly    24 EFYSSVDSMQDLAQVEEELLNATRSYVESQQKQLDFYRRYVEQIKREHEWATSQLKLDDYLGHPL 88
            ||..:..:..||.|::.||::...:|.|...::....:|..:::::....|..  :.::|||:||
  Fly    16 EFLDTESAKMDLMQLDVELIDNLMNYAEKIDEKASQLKRLAQELRQPLHSAKG--REEEYLGNPL 78

  Fly    89 HAFRLIKRLVRDW---DSLIFEPILANNAREEFRAFVEVLSRDL-GYPDQSELQGAIKGLARLQK 149
            |:|.||:.:.:||   :..:.:|:    ..||    ::.|.|.| ..|.|.:.:.|...:.|:.:
  Fly    79 HSFPLIRHMYQDWRYLEEFMKKPV----GEEE----IQFLRRKLPELPWQVDTEEASVSIFRIAE 135

  Fly   150 VYNLATSDLADGIIGGLNYGSDLRWRECYEIGVQLFDLGEYQRSLEWLQVAFILLRNSPREEKDA 214
            .|.:...|:|:|:|..:.:.|.|...:|:|:....|..|.::::|:|:.::...::
  Fly   136 TYGMMPWDMANGLIDNVRFNSTLPALDCFEVAKMYFKWGYFKQALQWITISKARMK--------- 191

  Fly   215 DHYLSDIREYASMANFE-LGNPKKAARLLS--------------QILESQPTHSAQQTQKYLESR 264
                   .||:.:  :| ||..::...||.              ::|..||..:........:.:
  Fly   192 -------EEYSGV--YEVLGMNRQDVALLQARCLVELDRRDEAHEVLLDQPDLADNSISLLDQFK 247

  Fly   265 VPGKNVQETKPSWFSNYTRLCQGRRLPEERSGDPLRCYLDGKRHAYFTLAPLQVEPVHLDPDINV 329
            .......::.|.....|.|||:....|   :...|.|..:....|:..||||::|.:.|:|.|.|
  Fly   248 ANPYEAIDSSPKLGEGYKRLCRSSFSP---NPSKLHCRYNSTTSAFLILAPLKMEEISLEPHIVV 309

  Fly   330 YHGMLSSKQILSIFEEAD----KEEMVRSAVAGSGGEGTVRDLRVSQQTWLDYKSPVMNSVGRII 390
            ||.:|..|.|..:...|:    ..||.         :....:.|.|.:|.|.  .|:::|:.:.:
  Fly   310 YHDILPDKDIQQLITLAEPLLKPTEMF---------DDNKNEARSSYRTPLG--GPLLDSLTQRM 363

  Fly   391 QFVSGFDMAGAEHMQVANYGVGGQYEPHPDYFEVNLPKNFE----GDRISTSMFYLSDVEQGGYT 451
            :.::|..:.....:.:..||.|..|..:.|:|:   .:|.|    |||::|.||||:|...||.|
  Fly   364 RDITGLQIRQGNPINIIKYGFGAPYTNYYDFFK---KRNSESKGFGDRMATFMFYLNDAPYGGAT 425

  Fly   452 VFTKLNVFLPPVKGALVMWHNLHRSLH-VDARTLHAGCPVIVGSKRIGNIWMH 503
            ||.:|||.:|..:|.::.|:||:...| ::..|:||.|||..|||.:...|:|
  Fly   426 VFPRLNVKVPAERGKVLFWYNLNGDTHDMEPTTMHAACPVFHGSKWVMTAWIH 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG2	NP_651801.1	P4Ha_N	28..163	CDD:285528	34/138 (25%)
		P4Hc	335..503	CDD:214780	53/176 (30%)
PH4alphaNE3	NP_651814.1	P4Ha_N	25..149	CDD:285528	34/133 (26%)
		P4Hc	316..478	CDD:214780	53/175 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461785
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28396
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	11	10.910