Protein Alignment PH4alphaSG2 and CG31013

DIOPT Version :10

• Sequence 1: NP_651801.1
• Gene: PH4alphaSG2 / 43623
• FlyBaseID: FBgn0039779
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_733394.3
• Gene: CG31013 / 326111
• FlyBaseID: FBgn0051013
• Length: 534
• Species: Drosophila melanogaster
• Alignment Length: 553
• Identity: 163/553 - (29%)
• Similarity: 259/553 - (46%)
• Gaps: 81/553 - (14%)

  Fly     6 CLYIGIFQLIIWVGVANGEFYSSVD--SMQDLAQVEEELLNATRSYVESQQKQLDFYRRYVEQIK 68
            ||.:.:|...:.:|....|...|:.  :|..|.::|::|::...:|..:.:::|:..|..:..|:
  Fly     7 CLLVMLFHSTLVLGHRPLEKSHSLSLVTMVPLLELEKKLIDNLENYTNALEQKLEIIRSQLLVIR 71

  Fly    69 REHEWATSQLKLDDYLGHPLHAFRLIKRLVRDWDSLIFEPILANNAREEFRAFVEVLSRDLGY-- 131
            .|:|  ..:.....||.:||:.|.:|:||.:||          .|.|:.....|.:......|
  Fly    72 AENE--KGRRNAISYLSNPLNGFSIIRRLHQDW----------INWRKYMEQPVGIWQLKAFYSW 124

  Fly   132 ----PDQSELQGAIKGLARLQKVYNLATSDLADGIIGGLNYGSDLRWRECYEIGVQLFDLGEYQR 192
                |.:.:|..|.:|:||:|..|:|...|..:|.|.|..|...:...:...:|..||.......
  Fly   125 KDELPTERDLWDACEGIARIQSTYDLKVGDFINGNINGKQYNDSMSTADILSVGAYLFMKNRPSD 189

  Fly   193 SLEWLQVA--------FILLRNSPREEKDADHYLSDIREYASMANFELGNPKKAARLLSQILESQ 249
            :::|||..        .|..|:.|.:|.||...|::       |..:..|..:|..||...|:.|
  Fly   190 AIQWLQEVPQRLQEELLIQPRHLPIKEVDALRLLAE-------AQIKDQNYSEALPLLHNCLKLQ 247

  Fly   250 PTHSA------QQTQKYLES---RVPGKNVQETKPSWFSNYTRL-CQGRRLPEERSGDPLRCYLD 304
            | |.|      ::|..::|:   :.|.:|.:...|  .:|..:| |.|   |.| |...|.|:.:
  Fly   248 P-HDARVLRLWKKTTDFIENQPDQSPTENKKRNVP--IANAFKLSCNG---PLE-SSTRLHCFYN 305

  Fly   305 GKRHAYFTLAPLQVEPVHLDPDINVYHGMLSSKQILSIFEEA---------DKEEMVRSAVAGSG 360
            .....:..||||:.|.:.|||.:.:||.:||:::|..:..:|         .||..|.....|
  Fly   306 FTTTPFLRLAPLKTEQIGLDPYVVLYHEVLSAREISMLIGKAAQNMKNTKIHKERAVPKKNRG-- 368

  Fly   361 GEGTVRDLRVSQQTWLDYKS-PVMNSVGRIIQFVSGFDMAGAEHMQVANYGVGGQYEPHPDYFEV 424
                    |.::..||..:| .:...:.|.|..::|||:|.:|..||.|||:||.|..|.|||:.
  Fly   369 --------RTAKGFWLKKESNELTKRITRRIMDMTGFDLADSEGFQVINYGIGGHYFLHMDYFDF 425

  Fly   425 NLPKNFE---------GDRISTSMFYLSDVEQGGYTVFTKLNVFLPPVKGALVMWHNLHRSLHVD 480
            ....:.:         ||||:|.:|||:||||||.|||..:..::.|..|..:.|:||....:.|
  Fly   426 ASSNHTDTRSRYSIDLGDRIATVLFYLTDVEQGGATVFGDVGYYVSPQAGTAIFWYNLDTDGNGD 490

  Fly   481 ARTLHAGCPVIVGSKRIGNIWMHSGYQEFRRPC 513
            .||.||.||||||||.:...|:....|.|.|||
  Fly   491 PRTRHAACPVIVGSKWVMTEWIREKRQIFIRPC 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG2	NP_651801.1	P4Ha_N	28..165	CDD:462433	37/144 (26%)
		CpoB	<178..263	CDD:441335	24/98 (24%)
		P4Hc	335..503	CDD:214780	66/186 (35%)
CG31013	NP_733394.3	P4Ha_N	31..162	CDD:462433	36/142 (25%)
		NrfG	<181..256	CDD:443378	22/82 (27%)
		TPR repeat	211..246	CDD:276809	11/41 (27%)
		P4Hc	336..513	CDD:214780	66/186 (35%)