Protein Alignment PH4alphaSG2 and P4ha3

DIOPT Version :9

• Sequence 1: NP_651801.1
• Gene: PH4alphaSG2 / 43623
• FlyBaseID: FBgn0039779
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: XP_006508007.1
• Gene: P4ha3 / 320452
• MGIID: 2444049
• Length: 551
• Species: Mus musculus
• Alignment Length: 535
• Identity: 175/535 - (32%)
• Similarity: 258/535 - (48%)
• Gaps: 63/535 - (11%)

  Fly    26 YSSVDSMQDLAQVEEELLNATRSYVESQQKQLDFYRRYVEQIKREHEWATSQLKLDDYLGHPLHA 90
            :|::.|:......|..||...|.|:..::.:|....|:.:::...||    .||:.  :.:||.|
Mouse    29 FSALTSVARALAPERRLLGTLRRYLRGEEARLRDLTRFYDKVLSLHE----DLKIP--VVNPLLA 87

  Fly    91 FRLIKRLVRDWDSLIFEPILANNAREEFRAF---VEVLSRDLGYPDQSELQGAIKGLARLQKVYN 152
            |.|||||..||.:::.    :..|.|..||.   .|.:.:||  |...:|:||.:.|.|||.||.
Mouse    88 FTLIKRLQSDWRNVVH----SLEATENIRALKDGYEKVEQDL--PAFEDLEGAARALMRLQDVYM 146

  Fly   153 LATSDLADGIIGGLNYGS-----------DLRWRECYEIG--------VQL-FDLGEYQRSLEWL 197
            |....||.|:...:...|           .|...:|:::|        :|: :|.|:|..::.||
Mouse   147 LNVKGLARGVFQRVTGSSITDLYSPRQLFSLTADDCFQVGKPSCGSRSLQVAYDTGDYYHAIPWL 211

  Fly   198 QVAFILLRNSPREEKDADH-YLSDIREYASMANFELGNPKKAARLLSQILESQPTHS--AQQTQK 259
            :.|..|.|.:..|.|..|. .|.|..:|.:.|.|::||...|..|..:.|...|.:.  |:...|
Mouse   212 EEAVSLFRRAHGEWKTEDEASLEDALDYLAFACFQVGNVSCALSLSREFLVYSPDNKRMARNVLK 276

  Fly   260 Y------------LESRVPGKNVQETKPSWFSNYTRLCQ--GRRLPEERSGDPLRCYLDGKRHAY 310
            |            .|:.:...||...:..  ..|..|||  |.: |.......|.|..:.....|
Mouse   277 YERLLAENGHQMAAETAIQRPNVPHLQTR--DTYEGLCQTLGSQ-PTHYQIPSLYCSYETNSSPY 338

  Fly   311 FTLAPLQVEPVHLDPDINVYHGMLSSKQILSIFEEADKEEMVRSAVAGSGGEGTVRDLRVSQQTW 375
            ..|.|.:.|.|||.|.|.:||..:|.::...|.|.|  |..::.:|..||.:....:.|:|:..|
Mouse   339 LLLQPARKEVVHLRPLIALYHDFVSDEEAQKIRELA--EPWLQRSVVASGEKQLQVEYRISKSAW 401

  Fly   376 L-DYKSPVMNSVGRIIQFVSGFDMAG--AEHMQVANYGVGGQYEPHPDYF---EVNLPKNFEGDR 434
            | |...|::.::...|..::|.|:..  ||::||.|||:||.||||.|:.   ...|.:...|:|
Mouse   402 LKDTVDPMLVTLDHRIAALTGLDIQPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYRMKSGNR 466

  Fly   435 ISTSMFYLSDVEQGGYTVFTKLNVFLPPVKGALVMWHNLHRSLHVDARTLHAGCPVIVGSKRIGN 499
            ::|.|.|||.||.||.|.|...|..:|.||.|.:.|.|||||...|..||||||||:||.|.:.|
Mouse   467 VATFMIYLSSVEAGGATAFIYGNFSVPVVKNAALFWWNLHRSGEGDGDTLHAGCPVLVGDKWVAN 531

  Fly   500 IWMHSGYQEFRRPCN 514
            .|:|...|||||||:
Mouse   532 KWIHEYGQEFRRPCS 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG2	NP_651801.1	P4Ha_N	28..163	CDD:285528	44/137 (32%)
		P4Hc	335..503	CDD:214780	70/173 (40%)
P4ha3	XP_006508007.1	P4Ha_N	31..157	CDD:369820	44/137 (32%)
		P4Hc	363..535	CDD:214780	70/173 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839340
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4458
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.790