Protein Alignment PH4alphaSG2 and CG31524

DIOPT Version :9

• Sequence 1: NP_651801.1
• Gene: PH4alphaSG2 / 43623
• FlyBaseID: FBgn0039779
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_733379.2
• Gene: CG31524 / 318781
• FlyBaseID: FBgn0051524
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 551
• Identity: 150/551 - (27%)
• Similarity: 255/551 - (46%)
• Gaps: 83/551 - (15%)

  Fly     7 LYIGIFQLIIWVG---VANGEFYSSVDSMQDLAQVEEELLNATRSYVESQQKQLDFYRRYVEQIK 68
            |::.||.|.:.:|   .....|..||.:|.||..:|::|::....|.|....:.:..|..::|::
  Fly     7 LFVVIFFLSLSMGQIEATQPRFARSVVNMDDLLNMEDDLVSKLEGYAEKLSYKANTIRWGIQQMR 71

  Fly    69 REHEWATSQLKLDDYLGHPLHAFRLIKRLVRDWDSLIFEPILANNAREEFRAFVEVLSRDLGY-- 131
            .:.:.:..:...|.:     :.:..|:.:..||  |:::..|..          .|:..:|.|
  Fly    72 EQLDKSKKEQSFDLF-----NRYSFIRHMQADW--LMWKQYLDK----------PVIRDELNYKQ 119

  Fly   132 ------PDQSELQGAIKGLARLQKVYNLATSDLADGIIGGLNYGSDLRWRECYEIGVQLFDLGEY 190
                  |.:.:|..|.:.:.|:|..|.:.::|:|:|.:.|:.|.|.|...:|..:|..|.:...:
  Fly   120 MDNLRMPQELDLFDASEAIRRMQATYAMLSNDIAEGFLDGVQYTSKLSPIDCLAMGRHLMNQSRW 184

  Fly   191 QRSLEWL------------QVAFILLRNSPREEKDADHYLSDIREYASMANFELGNPKKAARLLS 243
            ..:.:|:            |...||||...:.|  ....|..:|       ||..|.:.|.:...
  Fly   185 TIAEQWILAGIKAQDRKGPQTEMILLRGPTKAE--LFRTLGKVR-------FERRNEEGALKAYQ 240

  Fly   244 QILESQPTHSAQQTQKY--LESRV------------PGKNVQETKPSWFSNYTRLCQGRRLPEER 294
            ..|:..| |..:..|:|  |:.||            |..:::|.:      ....|.| |....|
  Fly   241 AALKHSP-HDLEIFQEYQNLKRRVLTLSPSEPIREEPNDDIEEME------LPPCCSG-RCEGPR 297

  Fly   295 SGDPLRCYLDGKRHAYFTLAPLQVEPVHLDPDINVYHGMLSSKQILSIFEEADKEEMVRSAVAGS 359
            ..:.|.|..:.....:..|||::.|.:.:||.:.:.|.|:|.|: .::...:.|.:::.|....:
  Fly   298 KLNRLYCVYNCVTAPFLRLAPIKTEILSVDPFVILLHDMVSHKE-GALIRSSSKNQILPSETVNA 361

  Fly   360 GGEGTVRDLRVSQQTWLDYKSPVMNSVGRIIQFV---SGFDMAGAEHMQVANYGVGGQYEPHPDY 421
            ..|..:...|.|:..|.|  |....:..::.|.:   :|.||..:|..||.|||:||.:|.|.|.
  Fly   362 ANEFEIAKFRTSKSVWFD--SDANEATLKLTQRLGEATGLDMKHSEPFQVINYGIGGVFESHFDT 424

  Fly   422 FEVNLPKNFEG--DRISTSMFYLSDVEQGGYTVFTKLNVFLPPVKGALVMWHNLHRS--LHVDAR 482
            ...:..:...|  ||::|::|||:||.|||.|.|..||:.:.|..|.::||:|||..  |||  |
  Fly   425 SLADEDRFVNGYIDRLATTLFYLNDVPQGGATHFPGLNITVFPKFGTVLMWYNLHTEGMLHV--R 487

  Fly   483 TLHAGCPVIVGSKRIGNIWMHSGYQEFRRPC 513
            |:|.|||||||||.:.:.|:....|||||||
  Fly   488 TMHTGCPVIVGSKWVVSKWIDDKGQEFRRPC 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG2	NP_651801.1	P4Ha_N	28..163	CDD:285528	29/142 (20%)
		P4Hc	335..503	CDD:214780	64/174 (37%)
CG31524	NP_733379.2	P4Ha_N	31..157	CDD:285528	29/142 (20%)
		TPR_11	215..>259	CDD:290150	12/53 (23%)
		TPR_2	216..249	CDD:285020	9/42 (21%)
		P4Hc	340..507	CDD:214780	62/171 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461787
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	10	9.900