DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaSG2 and phy-3

DIOPT Version :9

Sequence 1:	NP_651801.1	Gene:	PH4alphaSG2 / 43623	FlyBaseID:	FBgn0039779	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_507251.2	Gene:	phy-3 / 188624	WormBaseID:	WBGene00004026	Length:	318	Species:	Caenorhabditis elegans

Alignment Length:	244	Identity:	58/244 - (23%)
Similarity:	103/244 - (42%)	Gaps:	30/244 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   277 WFSNYTRLCQGRRLPEERSGDPLRC--YLDGKRHAYFTLAPLQVEPVHLDPDINVYHGMLSSKQ- 338
            |.::...||.......:...:...|  |:       :.:.|:.:|.:...|.:.:|..::|.:|
Worm    49 WSTDQLELCDDETKDTKWQKNDSICITYV-------YNMLPVDMEIISWAPTLVIYRNLMSPRQT 106

  Fly   339 --ILSIFEEADKEEMVRSAVAGSGGEGTVRDLRVSQQTWLDYKSPVMNSVGRIIQF-----VSGF 396
              .|:..|:.|. |:.:::..|:..|.|.|....|      :..|..::|...|:.     :.|.
Worm   107 ASFLNFIEQRDL-EIQKTSDFGTSIETTHRRANGS------FIPPEDSNVTVEIKMQAQKRIPGL 164

  Fly   397 DMAGAEHMQVANYGVGGQYEPHPDYFEVNLPKNFE------GDRISTSMFYLSDVEQGGYTVFTK 455
            ::..|||....:|..||.|..|.||.:....::::      |:||.|.:|.|...|:||.|||..
Worm   165 NLTVAEHFSALSYLPGGHYAVHYDYLDYRSKQDYDWWMNKTGNRIGTLIFVLKPAEKGGGTVFPS 229

  Fly   456 LNVFLPPVKGALVMWHNLHRSLHVDARTLHAGCPVIVGSKRIGNIWMHS 504
            :...:....|....|.|.......:..:.|.|||:..|.|.|..||:.:
Worm   230 IGSTVRANAGDAFFWFNAQADEEKEMLSNHGGCPIYEGRKVIATIWIRA 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG2	NP_651801.1	P4Ha_N	28..163	CDD:285528
PH4alphaSG2	NP_651801.1	P4Hc	335..503	CDD:214780	49/181 (27%)
phy-3	NP_507251.2	P4Hc	102..277	CDD:214780	49/181 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770