Protein Alignment PH4alphaSG2 and P4ha1

DIOPT Version :9

• Sequence 1: NP_651801.1
• Gene: PH4alphaSG2 / 43623
• FlyBaseID: FBgn0039779
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_001303300.1
• Gene: P4ha1 / 18451
• MGIID: 97463
• Length: 534
• Species: Mus musculus
• Alignment Length: 543
• Identity: 174/543 - (32%)
• Similarity: 276/543 - (50%)
• Gaps: 53/543 - (9%)

  Fly    15 IIWV----------GVANGEFYSSVDSMQDLAQVEEELLNATRSYVESQQKQLDFYRRYVEQIKR 69
            :|||          .:|:..|::|:..|.||...|::|:.:.:.|:::::.:|:..:::.|::.|
Mouse     1 MIWVVLMMAILLPQSLAHPGFFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDR 65

  Fly    70 EHEWATSQLKLDDYLGHPLHAFRLIKRLVRDWDSLIFEPILANNAREEFRAFVEVLSRDLGY-PD 133
            ....||..  .:.::|||::||:|:|||..:|..|  |.::..:..:   .|:..|:....| |:
Mouse    66 LTSTATKD--PEGFVGHPVNAFKLMKRLNTEWSEL--ENLILKDMSD---GFISNLTIQRQYFPN 123

  Fly   134 QSELQGAIKGLARLQKVYNLATSDLADGIIGGLNYGSDLRWRECYEIGVQLFDLGEYQRSLEWLQ 198
            ..:..||.|.|.|||..|||.|:.::.|.:.|:.:.|.|...:|:|:|...:...:|..:..|::
Mouse   124 DEDQVGAAKALFRLQDTYNLDTNTISKGNLPGVQHKSFLTAEDCFELGKVAYTEADYYHTELWME 188

  Fly   199 VAFILLRNSPREEKDADHYLSDIREYASMANFELGNPKKAARLLSQILESQPTHSAQQTQ----K 259
            .|...|........|.    ..:.:|.|.|.::.|:..||..|..::||..|.|......    :
Mouse   189 QALTQLEEGELSTVDK----VSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLVYFE 249

  Fly   260 YLESRVPGKNV--------QETKPS----------WFSNYTRLCQGRRLP-EERSGDPLRC-YLD 304
            |:.|:....|.        |:|.|.          ....|..||:|..:. ..|....|.| |.|
Mouse   250 YIMSKEKDANKSASGDQSDQKTAPKKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHD 314

  Fly   305 GKRHAYFTLAPLQVEPVHLDPDINVYHGMLSSKQILSIFEEADKEEMVRSAVAG-SGGEGTVRDL 368
            |.|:..|.|||.:.|.....|.|..:|.::|..:| .|.::..|..:.|:.|.. ..|:.|....
Mouse   315 GNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEI-EIVKDLAKPRLSRATVHDPETGKLTTAQY 378

  Fly   369 RVSQQTWLD-YKSPVMNSVGRIIQFVSGFDMAGAEHMQVANYGVGGQYEPHPDYFEVNLPKNFE- 431
            |||:..||. |:.||::.:...||.::|.|::.||.:||||||||||||||.|:...:.|..|.
Mouse   379 RVSKSAWLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRE 443

  Fly   432 ---GDRISTSMFYLSDVEQGGYTVFTKLNVFLPPVKGALVMWHNLHRSLHVDARTLHAGCPVIVG 493
               |:||:|.:||:|||..||.|||.::...:.|.||..|.|:||..|...|..|.||.|||:||
Mouse   444 LGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVG 508

  Fly   494 SKRIGNIWMHSGYQEFRRPCNLT 516
            :|.:.|.|:|...|||||||.|:
Mouse   509 NKWVSNKWLHERGQEFRRPCTLS 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG2	NP_651801.1	P4Ha_N	28..163	CDD:285528	40/135 (30%)
		P4Hc	335..503	CDD:214780	73/173 (42%)
P4ha1	NP_001303300.1	P4Ha_N	24..153	CDD:285528	40/135 (30%)
		TPR	205..238		10/32 (31%)
		P4Hc	345..518	CDD:214780	73/173 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820