DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaSG2 and C14E2.4

DIOPT Version :9

Sequence 1:	NP_651801.1	Gene:	PH4alphaSG2 / 43623	FlyBaseID:	FBgn0039779	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_001359861.1	Gene:	C14E2.4 / 182616	WormBaseID:	WBGene00015773	Length:	311	Species:	Caenorhabditis elegans

Alignment Length:	214	Identity:	55/214 - (25%)
Similarity:	88/214 - (41%)	Gaps:	30/214 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   316 LQVEPVHLDPDINVYHGMLSSKQILSIFEEADKEEMVRSAVAGSGGE----------GTVRDL-- 368
            :::|.:...|.:.:|..:.|.||:....|.....:|....|....||          ||:...
Worm    81 VRMEILSWSPPLVIYRDVFSKKQVSDYLELLKNLKMNEQKVVRDDGEIAYSTYRQANGTITPAHS 145

  Fly   369 RVSQQTWLDYKSPVMNSVGRIIQFVSGFDMAGAEHMQVANYGVGGQYEPHPDYF------EVNLP 427
            ....|:.:|..:          |.:..||....|.:...:|..||.|..|.|:.      :.|..
Worm   146 HAEAQSLMDTAT----------QLLPVFDFQYTEQISALSYIKGGHYALHTDFLTFANAEDSNRH 200

  Fly   428 KNFEGDRISTSMFYLSDVEQGGYTVFTKL-NVFLPPVKGALVMWHNLHRSLHVDARTLHAGCPVI 491
            ....|:|::|.:......|:||.|:|.:| |||... .|...:|.|.:.:|..:|::||.|||:.
Worm   201 FGEMGNRLATFIMVFKKAEKGGGTLFPQLGNVFRAN-PGDAFLWFNCNGNLEREAKSLHGGCPIR 264

  Fly   492 VGSKRIGNIWMHSGYQEFR 510
            .|.|.|..||:....|..|
Worm   265 AGEKIIATIWIRIFNQPIR 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG2	NP_651801.1	P4Ha_N	28..163	CDD:285528
PH4alphaSG2	NP_651801.1	P4Hc	335..503	CDD:214780	50/186 (27%)
C14E2.4	NP_001359861.1	P4Hc	100..276	CDD:214780	50/186 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770