Protein Alignment PH4alphaSG2 and phy-2

DIOPT Version :10

• Sequence 1: NP_651801.1
• Gene: PH4alphaSG2 / 43623
• FlyBaseID: FBgn0039779
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_502317.1
• Gene: phy-2 / 178170
• WormBaseID: WBGene00004025
• Length: 539
• Species: Caenorhabditis elegans
• Alignment Length: 533
• Identity: 164/533 - (30%)
• Similarity: 276/533 - (51%)
• Gaps: 38/533 - (7%)

  Fly    11 IFQLIIWVGVANGEFYSSVDSMQDLAQVEEELLNATRSYVESQQKQLDFYRRYVEQIKREHEWAT 75
            :..:.:..|:|:.:.::::..:|.:...|:::......|:|:::.:||..|||..:.  .|..|.
 Worm     4 VLLVCLLAGLAHADLFTAIADLQHMLGAEKDVTTIIDQYIEAERARLDDLRRYAHEY--VHRNAH 66

  Fly    76 SQLKLDDYLGHPLHAFRLIKRLVRDWDSLIFEPILANNAREEFRAFV--EVLSRDLGYPDQSELQ 138
            ::....:::.:|::|:.|||||..:|..:  |.|:.||....|...:  ..:..::.:|.:.:|.
 Worm    67 AESVGPEFVTNPINAYLLIKRLTTEWKKV--ENIMLNNKASTFLKNITDNRVRSEVKFPGEEDLS 129

  Fly   139 GAIKGLARLQKVYNLATSDLADGIIGGLNYGSDLRWRECYEIGVQLFDLGEYQRSLEWLQVAFIL 203
            ||...|.|||..|:|.|.||::|||||....:.|...:.:|:|...::..:|...|.|:|||.:.
 Worm   130 GAATALLRLQDTYSLDTLDLSNGIIGGEKVSNKLSGHDTFEVGRSAYNQKDYYHCLMWMQVALVK 194

  Fly   204 LRNS--PREEKDADHYLSDIREYASMANFELGNPKKAARLLSQILESQPTH-SAQQTQKYLESRV 265
            :.|.  |..|:      .:|.||.:.:.::.||.::|..|..::.:..|.| .|:...|:.|..:
 Worm   195 IENENPPTIEE------WEILEYLAYSLYQQGNVRRALSLTKRLAKIAPNHPRAKGNVKWYEDML 253

  Fly   266 PGKNVQETKPSWFSN------------YTRLCQGRRLP-EERSGDPLRCYLDGKR-HAYFTLAPL 316
            .||::....|...:.            |..||:|...| |.:..:.|||||  || ..:..|||:
 Worm   254 QGKDMVGDLPPIVNKRVEYDGIVERDAYEALCRGEIPPVEPKWKNKLRCYL--KRDKPFLKLAPI 316

  Fly   317 QVEPVHLDPDINVYHGMLSSKQILSIFEEADKEEMVRSAVAGS-GGEGTVRDLRVSQQTWLDYK- 379
            :||.:..||...::..::...:| .:.:|....::.|:.|..| .||......|:|:..||...
 Worm   317 KVEILRFDPLAVLFKNVIHDSEI-EVIKELASPKLKRATVQNSKTGELEHATYRISKSAWLKGDL 380

  Fly   380 SPVMNSVGRIIQFVSGFDMAGAEHMQVANYGVGGQYEPHPDYF---EVNLPKNFE-GDRISTSMF 440
            .||::.|.|.|:..:..:.|.:|.:||||||:||.|:||.|:.   |.|..|... |:||:|.:|
 Worm   381 DPVIDRVNRRIEDFTNLNQATSEELQVANYGLGGHYDPHFDFARKEEKNAFKTLNTGNRIATVLF 445

  Fly   441 YLSDVEQGGYTVFTKLNVFLPPVKGALVMWHNLHRSLHVDARTLHAGCPVIVGSKRIGNIWMHSG 505
            |:|..|:||.|||..|...:.|.|...:.|:||.|....|.||.||.|||::|.|.:.|.|:|..
 Worm   446 YMSQPERGGATVFNHLGTAVFPSKNDALFWYNLRRDGEGDLRTRHAACPVLLGVKWVSNKWIHEK 510

  Fly   506 YQEFRRPCNLTSD 518
            .|||.|||.|..:
 Worm   511 GQEFTRPCGLEEE 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG2	NP_651801.1	P4Ha_N	28..165	CDD:462433	40/138 (29%)
		CpoB	<178..263	CDD:441335	22/87 (25%)
		P4Hc	335..503	CDD:214780	65/173 (38%)
phy-2	NP_502317.1	P4Ha_N	21..156	CDD:462433	40/138 (29%)
		P4Hc	335..508	CDD:214780	65/173 (38%)