DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaSG2 and LOC110438249

DIOPT Version :9

Sequence 1:	NP_651801.1	Gene:	PH4alphaSG2 / 43623	FlyBaseID:	FBgn0039779	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	XP_021324927.1	Gene:	LOC110438249 / 110438249	-ID:	-	Length:	229	Species:	Danio rerio

Alignment Length:	241	Identity:	93/241 - (38%)
Similarity:	133/241 - (55%)	Gaps:	27/241 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   284 LCQGRRLPEERSGDPLRCYLDGKRHAYFTLAPLQVEPVHLD-PDINVYHGMLSSKQILSIFEEAD 347
            :|:.||    ..|:||..:               .|.|..| |.|..||..||..:|.:| :...
Zfish    10 VCRYRR----GRGNPLMLF---------------KEEVEWDQPMILRYHDFLSEGEIDTI-KTLA 54

  Fly   348 KEEMVRSAVAGS-GGEGTVRDLRVSQQTWL-DYKSPVMNSVGRIIQFVSGFDMAGAEHMQVANYG 410
            :.::.|:.|..: .|:......||||..|| :.:.||:..|.:.|..|:|.::..||.:|:||||
Zfish    55 RPKLSRAQVIDAVSGKRVSAASRVSQSAWLYEDEDPVVTQVNQRIADVTGLELQTAESLQIANYG 119

  Fly   411 VGGQYEPHPDYFEVNLPKNFE--GDRISTSMFYLSDVEQGGYTVFTKLNVFLPPVKGALVMWHNL 473
            :|||||||.|....| ..:|:  |.||:|.:.|:|||:.||.|||..:...|.|.:|:.|:|.||
Zfish   120 IGGQYEPHYDSKLTN-DSDFQLRGGRIATVLIYMSDVDIGGATVFPDVGAALQPKRGSAVLWFNL 183

  Fly   474 HRSLHVDARTLHAGCPVIVGSKRIGNIWMHSGYQEFRRPCN-LTSD 518
            .|:.:.|.|||||.|||.||||.:.|.|:.:..|||||.|: :.||
Zfish   184 LRNGNEDIRTLHAACPVFVGSKWVANKWIRTYGQEFRRKCSTIKSD 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG2	NP_651801.1	P4Ha_N	28..163	CDD:285528
PH4alphaSG2	NP_651801.1	P4Hc	335..503	CDD:214780	71/171 (42%)
LOC110438249	XP_021324927.1	PLN00052	28..218	CDD:177683	78/191 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010