DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon99Fii and C1s2

DIOPT Version :9

Sequence 1:	NP_651799.1	Gene:	Jon99Fii / 43621	FlyBaseID:	FBgn0039777	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_776289.2	Gene:	C1s2 / 317677	MGIID:	3644269	Length:	694	Species:	Mus musculus

Alignment Length:	272	Identity:	77/272 - (28%)
Similarity:	114/272 - (41%)	Gaps:	50/272 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 PVKDVKIQGRITNGYPAYEGKVPYIVGLLFSGNGNWWCGGSIIGNTWVLTAAHCTNGAS------ 86
            |.:..::|.:|..|.||.....|:.|   |..:..  .||::|...|||||||.....|
Mouse   434 PTEPFQVQQKIFGGQPAKIENFPWQV---FFNHPT--AGGALINEYWVLTAAHVVEKNSDPSMYA 493

  Fly    87 GVTINYGASLRN-QPQYTHWVGSGNFVQHHHYNSG-------NLHNDISLIRTPH-VDFWHLVNK 142
            |:|....|.|.| |..||..|     :.|..:...       |..|||:|::... |......:.
Mouse   494 GITALRLADLENAQRLYTKRV-----IIHPGWKEDDDLNPRTNFDNDIALVQLKDPVKMGPKFSP 553

  Fly   143 VELPSYNDRYQDYAGWWAVASGWGGT--------YDGSPLPDWLQAVDVQIMSQSDCSR--SWSL 197
            :.||..:..|....|...:.||||.|        ..|:.:|........|:..::..:|  .:.:
Mouse   554 ICLPGTSSEYNLSPGDMGLISGWGRTEKRLHVINLRGAKVPVTSLETCKQVKEENPTARPEDYVI 618

  Fly   198 HDNMICINTNGGKSTCGGDSGG------PLVTHEGNRLVGVTSFVSSAGCQSGAPAVFSRVTGYL 256
            .|||||....|..| |.|||||      |.|......:.|:.|:    |.:.||..|:::|..|:
Mouse   619 TDNMICAGEKGVDS-CKGDSGGAFAFQVPNVKAPKFYVAGLVSW----GKKCGAYGVYTKVKNYV 678

  Fly   257 DWI----RDNTG 264
            |||    ::|:|
Mouse   679 DWILKTMQENSG 690

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon99Fii	NP_651799.1	Tryp_SPc	37..259	CDD:214473	71/252 (28%)
Jon99Fii	NP_651799.1	Tryp_SPc	38..262	CDD:238113	73/258 (28%)
C1s2	NP_776289.2	CUB	24..135	CDD:238001
		FXa_inhibition	149..177	CDD:291342
		CUB	181..293	CDD:278839
		CCP	300..361	CDD:153056
		CCP	365..428	CDD:153056
		Tryp_SPc	443..681	CDD:214473	71/252 (28%)
		Tryp_SPc	444..684	CDD:238113	73/254 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000