DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaEFB and AT-P4H-1

DIOPT Version :9

Sequence 1:	NP_733371.1	Gene:	PH4alphaEFB / 43620	FlyBaseID:	FBgn0039776	Length:	550	Species:	Drosophila melanogaster
Sequence 2:	NP_181836.1	Gene:	AT-P4H-1 / 818910	AraportID:	AT2G43080	Length:	283	Species:	Arabidopsis thaliana

Alignment Length:	247	Identity:	73/247 - (29%)
Similarity:	119/247 - (48%)	Gaps:	35/247 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   312 PSPSDLRSLRCRYVTN--------RVPFLRLGPLKLEEVHADPYIVIYHDAMYDSEIDLIKRMAR 368
            ||...||....||:.:        ....||:|.:|.|.|...|.|::.||.:...|.:.:|.:||
plant    42 PSLRGLRGQNTRYLRDVSRWANDKDAELLRIGNVKPEVVSWSPRIIVLHDFLSPEECEYLKAIAR 106

  Fly   369 PRFRRATVQNSVTGALETANYRISKSAWLKTQEDR---VIETVVQRTADMTGLDMDSAEELQVVN 430
            ||.:.:||.:..||....::.|.|...:| |..:|   :|:.:.:|.|..:.:..::.|.:||:.
plant   107 PRLQVSTVVDVKTGKGVKSDVRTSSGMFL-THVERSYPIIQAIEKRIAVFSQVPAENGELIQVLR 170

  Fly   431 YGIGGHYEPHFDFARKEEQRAFEGLNL---GNRIATVLFYMSDVEQGGATVF------------- 479
            |.....|:||.|:..       :..||   |.|:||:|.|::|..:||.|.|
plant   171 YEPQQFYKPHHDYFA-------DTFNLKRGGQRVATMLMYLTDDVEGGETYFPLAGDGDCTCGGK 228

  Fly   480 TSLHTALFPKKGTAAFWMNLHRDGQGDVRTRHAACPVLTGTKWVSNKWIHER 531
            .....::.|.||.|..:.::..|||.|.|:.|..|.||:|.||.:.||:.::
plant   229 IMKGISVKPTKGDAVLFWSMGLDGQSDPRSIHGGCEVLSGEKWSATKWMRQK 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaEFB	NP_733371.1	P4Ha_N	28..159	CDD:285528
PH4alphaEFB	NP_733371.1	P4Hc	356..529	CDD:214780	57/191 (30%)
AT-P4H-1	NP_181836.1	PLN00052	80..281	CDD:177683	62/209 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.960