Protein Alignment PH4alphaEFB and p4ha3

DIOPT Version :9

• Sequence 1: NP_733371.1
• Gene: PH4alphaEFB / 43620
• FlyBaseID: FBgn0039776
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: XP_021322008.1
• Gene: p4ha3 / 563281
• ZFINID: ZDB-GENE-041010-4
• Length: 616
• Species: Danio rerio
• Alignment Length: 549
• Identity: 196/549 - (35%)
• Similarity: 287/549 - (52%)
• Gaps: 43/549 - (7%)

  Fly     1 MAADWRLMLLLGILLLVGGPANGEVYTALAEMEELLETESVLITNLEGYIRVQEDKLNFLKNKMD 65
            |.:.:.|.::| .||.:...:.||::|::..:.:.:..|..||.:|..||..:..:|..:|....
Zfish     1 MCSCFTLFIVL-YLLNMPDESFGEMFTSMLSVNQAVSAERKLIDHLIIYIEHEAQRLEDIKRFFS 64

  Fly    66 EYQREHSDASHDITAYVSNPINAYLLTKRLTTDWRQVENLMEHDVGTDFLQNITQYRSL-LKFPS 129
            .....|....::.:..::|||.|:.|.|||.::|..|.:..|.:.....|:.  .||.: ...|.
Zfish    65 RVTSLHDGIYNEPSDPIANPIAAFKLVKRLKSEWLNVVHSTEAEENIKVLRE--DYRRMESSLPK 127

  Fly   130 DEDLNGAAVALLRLQDTYQLDTSSVARGKLNGI---------QYSTEMSSDDCFELGRQSYVNHD 185
            .|||.|||..|:||||.|.|...|:.||....|         ..|..:|.||||.:|:.:|...|
Zfish   128 LEDLRGAAHGLMRLQDVYNLHVESLVRGHFQQISDPVDFYKLSVSDMLSGDDCFLVGKVAYDLED 192

  Fly   186 YYHTVLWMNEAMARMLE----EPTNHTQSFTKADILEYLAFSTYKEGNIESALTMTNELLQLLPH 246
            |||:|||..||: |:..    .|.|..   |..|.|::||||.:|.|||..||:::.|||...|.
Zfish   193 YYHSVLWFEEAV-RLFRGTEWSPENEG---TLEDALDHLAFSHFKTGNISHALSLSRELLLHDPM 253

  Fly   247 HERANGNKRFYEKEIAQQLQLRKMKGDDGTDEMPKSDLPVAKSDPAIFDMTERRAYEMLCRGE-L 310
            :.|.:.|...|||.:              .:.:|.:...:....|....:..|.|||.||:.: .
Zfish   254 NRRVHFNVEKYEKLL--------------NENLPATSSGLTLKRPDGIYLRTRNAYEQLCQTKGS 304

  Fly   311 KPSPSDLRSLRCRYVTNRVPFLRLGPLKLEEVHADPYIVIYHDAMYDSEIDLIKRMARPRFRRAT 375
            :|...:..||.|.|.||..|.|.|.|::.|.:...||:|::|..:..:|...|::.|.|..||:.
Zfish   305 QPKHFENPSLFCDYFTNGSPALFLQPIRREIISLQPYVVLFHGFVTQAEAKNIRKYAMPGLRRSV 369

  Fly   376 VQNSVTGALETANYRISKSAWLKTQEDRVIETVVQRTADMTGLDMDS--AEELQVVNYGIGGHYE 438
            |.:.:..|  ||.||||||||||.....|:..:.||...:|||::..  ||.|||||||||||||
Zfish   370 VASGMNQA--TAEYRISKSAWLKESAHEVVGKLDQRITLVTGLNVQPPYAEYLQVVNYGIGGHYE 432

  Fly   439 PHFDFARKEEQRAFEGLNLGNRIATVLFYMSDVEQGGATVFTSLHTALFPKKGTAAFWMNLHRDG 503
            ||||.|..:....:. |..|||:||::.|:|.|:.||:|.|...:.::...:..|.||.|||::|
Zfish   433 PHFDHATSDSSPLYR-LKTGNRVATIMIYLSPVQAGGSTAFIYANFSVPVVQNAALFWWNLHKNG 496

  Fly   504 QGDVRTRHAACPVLTGTKW--VSNKWIHE 530
            ||:|.|.||.|||:.|.||  ..||..|:
Zfish   497 QGNVDTLHAGCPVIVGNKWGMFKNKNFHK 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaEFB	NP_733371.1	P4Ha_N	28..159	CDD:285528	40/131 (31%)
		P4Hc	356..529	CDD:214780	80/176 (45%)
p4ha3	XP_021322008.1	P4Ha_N	27..157	CDD:311993	40/131 (31%)
		P4Hc	350..519	CDD:214780	78/171 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583394
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52324
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.860