Protein Alignment PH4alphaEFB and p4ha1a

DIOPT Version :10

• Sequence 1: NP_733371.1
• Gene: PH4alphaEFB / 43620
• FlyBaseID: FBgn0039776
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: XP_073773811.1
• Gene: p4ha1a / 562774
• ZFINID: ZDB-GENE-040724-91
• Length: 603
• Species: Danio rerio
• Alignment Length: 553
• Identity: 259/553 - (46%)
• Similarity: 359/553 - (64%)
• Gaps: 24/553 - (4%)

  Fly     5 WRLMLL--------LGILLLVGGPANGEVYTALAEMEELLETESVLITNLEGYIRVQEDKLNFLK 61
            |:.:::        |.|.||....|:.:.:|::..|.:||.||..|:|:|:.||:.:|.||..:|
Zfish    59 WQSVMMGVRSVCCFLLISLLKSSSAHSDFFTSIGHMTDLLFTEKDLVTSLKDYIKAEESKLEQVK 123

  Fly    62 NKMDEYQREHSDASHDITAYVSNPINAYLLTKRLTTDWRQVENLMEHDVGTDFLQNITQYRSLLK 126
            ...::.....:.|..|...::.:|:||:.|.|||.|:|.:||:|:..|:...|:.|:|..|..
Zfish   124 QWAEKLDALTATAVQDPEGFLGHPVNAFKLMKRLNTEWGEVEDLVLKDMSDGFISNLTIQRQY-- 186

  Fly   127 FPSDEDLNGAAVALLRLQDTYQLDTSSVARGKL----NGIQYSTEMSSDDCFELGRQSYVNHDYY 187
            ||:|||.||||.|||||||||:|||.:::.|.|    .|:.|.:.::.:||||||:.:|.:.|||
Zfish   187 FPNDEDQNGAAKALLRLQDTYKLDTQTISSGDLPGVNTGLPYKSTLTVEDCFELGKIAYSDADYY 251

  Fly   188 HTVLWMNEAMARMLEEPTNHTQSFTKADILEYLAFSTYKEGNIESALTMTNELLQLLPHHERANG 252
            ||.|||.:|: :.|:|  ....|...|..|:||::|.|::|.:|.||..|..||.:.|.|:||.|
Zfish   252 HTELWMAQAL-KQLDE--GEESSVEIATALDYLSYSVYQQGELERALEYTKRLLTVEPEHQRALG 313

  Fly   253 NKRFYEKEIAQQLQLRKMKGDDGTDEMPKSDLPVAKSDPAIFDMTERRAYEMLCRGE-LKPSPSD 316
            |.::::.::|:|   :|.:.:..|.|..|.:...  ||.....:.|:|.||.||||| |:.:|..
Zfish   314 NLKYFDYQLAKQ---KKAEKEQSTKEESKKEQET--SDGKKEYLPEKRKYEKLCRGEGLRMTPRR 373

  Fly   317 LRSLRCRYVT-NRVPFLRLGPLKLEEVHADPYIVIYHDAMYDSEIDLIKRMARPRFRRATVQNSV 380
            .:.|.|||.. ||.||..:||:|.|:....|.|:.||:.:.:.||:.||.:::||.||||:.|.:
Zfish   374 QKHLFCRYFNGNRHPFYTIGPVKQEDEWDRPRIIRYHEIITEQEIEKIKELSKPRLRRATISNPI 438

  Fly   381 TGALETANYRISKSAWLKTQEDRVIETVVQRTADMTGLDMDSAEELQVVNYGIGGHYEPHFDFAR 445
            ||.||||:|||||||||...|..|::.:.||..|:|||::.:||||||.|||:||.|||||||.|
Zfish   439 TGVLETAHYRISKSAWLAAYEHPVVDRINQRIEDITGLNVKTAEELQVANYGVGGQYEPHFDFGR 503

  Fly   446 KEEQRAFEGLNLGNRIATVLFYMSDVEQGGATVFTSLHTALFPKKGTAAFWMNLHRDGQGDVRTR 510
            |:|..||:.|..||||||.|||||||..||||||..:..|:.|.||||.||.||...|:||..||
Zfish   504 KDEPDAFKELGTGNRIATWLFYMSDVAAGGATVFPEVGAAVKPLKGTAVFWYNLFPSGEGDYSTR 568

  Fly   511 HAACPVLTGTKWVSNKWIHERGQEFRRPCDLEE 543
            |||||||.|.|||||||||||||||||||.|:|
Zfish   569 HAACPVLVGNKWVSNKWIHERGQEFRRPCGLKE 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaEFB	NP_733371.1	P4Ha_N	28..161	CDD:462433	56/136 (41%)
		P4Hc	356..529	CDD:214780	107/172 (62%)
p4ha1a	XP_073773811.1	None