Protein Alignment PH4alphaEFB and CG31013

DIOPT Version :9

• Sequence 1: NP_733371.1
• Gene: PH4alphaEFB / 43620
• FlyBaseID: FBgn0039776
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_733394.3
• Gene: CG31013 / 326111
• FlyBaseID: FBgn0051013
• Length: 534
• Species: Drosophila melanogaster
• Alignment Length: 542
• Identity: 188/542 - (34%)
• Similarity: 275/542 - (50%)
• Gaps: 37/542 - (6%)

  Fly     7 LMLLLGILLLVGGPANGEVYTALAEMEELLETESVLITNLEGYIRVQEDKLNFLKNKMDEYQREH 71
            :||....|:|...|.......:|..|..|||.|..||.|||.|....|.||..:::::...:.|:
  Fly    10 VMLFHSTLVLGHRPLEKSHSLSLVTMVPLLELEKKLIDNLENYTNALEQKLEIIRSQLLVIRAEN 74

  Fly    72 SDASHDITAYVSNPINAYLLTKRLTTDWRQVENLMEHDVGTDFLQNITQYRSLLKFPSDEDLNGA 136
            .....:..:|:|||:|.:.:.:||..||......||..||...|:....::.  :.|::.||..|
  Fly    75 EKGRRNAISYLSNPLNGFSIIRRLHQDWINWRKYMEQPVGIWQLKAFYSWKD--ELPTERDLWDA 137

  Fly   137 AVALLRLQDTYQLDTSSVARGKLNGIQYSTEMSSDDCFELGRQSYVNHDYYHTVLWMNEAMARML 201
            ...:.|:|.||.|.......|.:||.||:..||:.|...:|...::.:.....:.|:.|...|:.
  Fly   138 CEGIARIQSTYDLKVGDFINGNINGKQYNDSMSTADILSVGAYLFMKNRPSDAIQWLQEVPQRLQ 202

  Fly   202 EE---PTNHTQSFTKADILEYLAFSTYKEGNIESALTMTNELLQLLPHHERANGNKRFYEKEIAQ 263
            ||   ...|. ...:.|.|..||.:..|:.|...||.:.:..|:|.||..|.   .|.::|
  Fly   203 EELLIQPRHL-PIKEVDALRLLAEAQIKDQNYSEALPLLHNCLKLQPHDARV---LRLWKK---- 259

  Fly   264 QLQLRKMKGDDGTDEMPKSDLPVAKSDPAIFDMTERRAYEMLCRGELKPSPSDLRSLRCRYVTNR 328
            .....:.:.|....|..|.::|:|            .|:::.|.|.|:.|    ..|.|.|....
  Fly   260 TTDFIENQPDQSPTENKKRNVPIA------------NAFKLSCNGPLESS----TRLHCFYNFTT 308

  Fly   329 VPFLRLGPLKLEEVHADPYIVIYHDAMYDSEIDLIKRMARPRFRRATVQNSVTGALETANY-RIS 392
            .|||||.|||.|::..|||:|:||:.:...||.::...|....:...:...  .|:...|. |.:
  Fly   309 TPFLRLAPLKTEQIGLDPYVVLYHEVLSAREISMLIGKAAQNMKNTKIHKE--RAVPKKNRGRTA 371

  Fly   393 KSAWLKTQEDRVIETVVQRTADMTGLDMDSAEELQVVNYGIGGHYEPH---FDFARKE--EQRAF 452
            |..|||.:.:.:.:.:.:|..||||.|:..:|..||:||||||||..|   ||||...  :.|:.
  Fly   372 KGFWLKKESNELTKRITRRIMDMTGFDLADSEGFQVINYGIGGHYFLHMDYFDFASSNHTDTRSR 436

  Fly   453 EGLNLGNRIATVLFYMSDVEQGGATVFTSLHTALFPKKGTAAFWMNLHRDGQGDVRTRHAACPVL 517
            ..::||:||||||||::||||||||||..:...:.|:.|||.||.||..||.||.|||||||||:
  Fly   437 YSIDLGDRIATVLFYLTDVEQGGATVFGDVGYYVSPQAGTAIFWYNLDTDGNGDPRTRHAACPVI 501

  Fly   518 TGTKWVSNKWIHERGQEFRRPC 539
            .|:|||..:||.|:.|.|.|||
  Fly   502 VGSKWVMTEWIREKRQIFIRPC 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaEFB	NP_733371.1	P4Ha_N	28..159	CDD:285528	40/130 (31%)
		P4Hc	356..529	CDD:214780	79/178 (44%)
CG31013	NP_733394.3	P4Ha_N	31..160	CDD:285528	40/130 (31%)
		TPR_11	178..248	CDD:290150	17/70 (24%)
		TPR repeat	211..246	CDD:276809	10/35 (29%)
		P4Hc	336..513	CDD:214780	79/178 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461820
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	10	9.900