DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaEFB and LOC110438249

DIOPT Version :9

Sequence 1:	NP_733371.1	Gene:	PH4alphaEFB / 43620	FlyBaseID:	FBgn0039776	Length:	550	Species:	Drosophila melanogaster
Sequence 2:	XP_021324927.1	Gene:	LOC110438249 / 110438249	-ID:	-	Length:	229	Species:	Danio rerio

Alignment Length:	230	Identity:	119/230 - (51%)
Similarity:	149/230 - (64%)	Gaps:	11/230 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   313 SPSDLRSLRCRYVTNRVPFLRLGPLKL--EEVHAD-PYIVIYHDAMYDSEIDLIKRMARPRFRRA 374
            :|...|.|.|||...|.     .||.|  |||..| |.|:.|||.:.:.|||.||.:|||:..||
Zfish     2 TPQRERKLVCRYRRGRG-----NPLMLFKEEVEWDQPMILRYHDFLSEGEIDTIKTLARPKLSRA 61

  Fly   375 TVQNSVTGALETANYRISKSAWLKTQEDRVIETVVQRTADMTGLDMDSAEELQVVNYGIGGHYEP 439
            .|.::|:|...:|..|:|:||||...||.|:..|.||.||:|||::.:||.||:.||||||.|||
Zfish    62 QVIDAVSGKRVSAASRVSQSAWLYEDEDPVVTQVNQRIADVTGLELQTAESLQIANYGIGGQYEP 126

  Fly   440 HFDFARKEEQRAFEGLNLGNRIATVLFYMSDVEQGGATVFTSLHTALFPKKGTAAFWMNLHRDGQ 504
            |:| ::......|:  ..|.||||||.|||||:.||||||..:..||.||:|:|..|.||.|:|.
Zfish   127 HYD-SKLTNDSDFQ--LRGGRIATVLIYMSDVDIGGATVFPDVGAALQPKRGSAVLWFNLLRNGN 188

  Fly   505 GDVRTRHAACPVLTGTKWVSNKWIHERGQEFRRPC 539
            .|:||.||||||..|:|||:||||...||||||.|
Zfish   189 EDIRTLHAACPVFVGSKWVANKWIRTYGQEFRRKC 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaEFB	NP_733371.1	P4Ha_N	28..159	CDD:285528
PH4alphaEFB	NP_733371.1	P4Hc	356..529	CDD:214780	92/172 (53%)
LOC110438249	XP_021324927.1	PLN00052	28..218	CDD:177683	101/192 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010