Protein Alignment PH4alphaEFB and p4ha3

DIOPT Version :9

• Sequence 1: NP_733371.1
• Gene: PH4alphaEFB / 43620
• FlyBaseID: FBgn0039776
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: XP_031752143.1
• Gene: p4ha3 / 100495824
• XenbaseID: XB-GENE-962355
• Length: 547
• Species: Xenopus tropicalis
• Alignment Length: 566
• Identity: 204/566 - (36%)
• Similarity: 294/566 - (51%)
• Gaps: 68/566 - (12%)

  Fly     5 WRLMLLLGILLLVGGPANGEVYTALAEMEELLETESVLITNLEGYIRVQEDKLNFLKNKMDEYQR 69
            |.|:|.:..|..:  .|..::|:::|.:::.:..|..|:.:|..|::.:..:|:.|:...::.|.
 Frog    13 WPLLLCVSWLHWL--HAGADMYSSMASIQQAVGMEGALLQHLGQYLQQETQRLSDLRRFYEKVQA 75

  Fly    70 EHSDASHDITAYVSNPINAYLLTKRLTTDWRQVENLMEHDVGTDFLQNITQYRSLLK--FPSDED 132
            .|......    |.:||.||.|.|||.::|.   |::......:.:|.:.:....:|  .|:.||
 Frog    76 SHQAGGPP----VQDPILAYTLLKRLQSEWM---NVVHSSEANENIQALKEGYEKVKQDLPAPED 133

  Fly   133 LNGAAVALLRLQDTYQLDTSSVARGK-----------LNGIQYSTEMSSDDCFELGRQSYVNHDY 186
            :.|||.||:||||.|.|:.:.:|||.           |....:.:.||:||||.:|:.:|...||
 Frog   134 VEGAAKALMRLQDVYSLNVNGLARGMFQRSSSSDTKLLYNPPHLSIMSADDCFHIGKVAYDMEDY 198

  Fly   187 YHTVLWMNEAMARM--------------LEEPTNHTQSFTKADILEYLAFSTYKEGNIESALTMT 237
            ||::.|:.||::|.              |||            .|:|||||.||.|||..||.::
 Frog   199 YHSIPWLEEAVSRFRGSYGNWRTEDEGSLEE------------ALDYLAFSYYKAGNISHALDLS 251

  Fly   238 NELLQLLPHHERANGNKRFYEKEIAQQLQLRKMKGDDGTDEMPKSDLPVAKSDPAIFDMTERRAY 302
            .|.|...|.:.|...|...||     |:.......|...:||       ....|.:..:..|..|
 Frog   252 RECLLYDPDNGRLARNIAKYE-----QILYESPTADADAEEM-------KLQRPNVTHLKTRDLY 304

  Fly   303 EMLCR--GELKPSPSDLRSLRCRYVTNRVPFLRLGPLKLEEVHADPYIVIYHDAMYDSEIDLIKR 365
            |.||:  |. :|:..:...:.|.|.||..|:|.|.|:|.|.|...|.:|:|||.:.|.|.:.||.
 Frog   305 EGLCQTLGS-QPTSYEDPHMSCMYDTNSHPYLLLQPMKKEIVSLRPQVVLYHDFVSDLEAEKIKE 368

  Fly   366 MARPRFRRATVQNSVTGALETANYRISKSAWLKTQEDRVIETVVQRTADMTGLDMDS--AEELQV 428
            :|.|...|:.|.:....|  .|.||||||||||......::.:..|.:.:|||:...  ||.|||
 Frog   369 LASPWLHRSVVASGEKQA--EAEYRISKSAWLKDTIHPFVQNLDTRISAVTGLNAHPPYAEYLQV 431

  Fly   429 VNYGIGGHYEPHFDFARKEEQRAFEGLNLGNRIATVLFYMSDVEQGGATVFTSLHTALFPKKGTA 493
            ||||||||||||||.|...:...:. .|.|||:||.:.|:|.|:.||:|.|...:.:....|..|
 Frog   432 VNYGIGGHYEPHFDHATSRKSPLYR-TNTGNRLATFMIYLSHVDLGGSTAFVFANFSSPVVKNAA 495

  Fly   494 AFWMNLHRDGQGDVRTRHAACPVLTGTKWVSNKWIHERGQEFRRPC 539
            .||.||||:|.||..|.||.|||:.|:|||:||||||.||||.|||
 Frog   496 VFWWNLHRNGLGDEDTLHAGCPVIIGSKWVANKWIHEFGQEFHRPC 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaEFB	NP_733371.1	P4Ha_N	28..159	CDD:285528	39/143 (27%)
		P4Hc	356..529	CDD:214780	81/174 (47%)
p4ha3	XP_031752143.1	P4Ha_N	35..>104	CDD:400573	19/75 (25%)
		TPR repeat	182..210	CDD:276809	13/27 (48%)
		TPR repeat	215..257	CDD:276809	18/53 (34%)
		P4Hc	359..531	CDD:214780	81/174 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000