DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CDase and AT2G38010

DIOPT Version :9

Sequence 1:	NP_001263109.1	Gene:	CDase / 43618	FlyBaseID:	FBgn0039774	Length:	704	Species:	Drosophila melanogaster
Sequence 2:	NP_973628.1	Gene:	AT2G38010 / 818379	AraportID:	AT2G38010	Length:	792	Species:	Arabidopsis thaliana

Alignment Length:	798	Identity:	293/798 - (36%)
Similarity:	423/798 - (53%)	Gaps:	120/798 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FLAFLAVSFLCGLVSATYKVGVGRADITGPPVEINFMGYANIKQVGRGIHTRVFARAFVVEDEKG 72
            |:.||.:..|...|.| |.:|||..|||||..::|.|||||..|:..|||.|:.||||:|.:.:|
plant    10 FILFLLLLLLSRTVYA-YLIGVGSYDITGPAADVNMMGYANSDQIASGIHFRLRARAFIVAEPQG 73

  Fly    73 NRVAFVSADAGMMGYGLKREVIKRLQARYGNIYHNDNVAISGTHTHGAPGGFLMHLLYDISILGF 137
            |||.||:.||.|....:..:|::||:||||.:|...||||||.|||..|||:|.::.|.::.|||
plant    74 NRVVFVNLDACMASQIVTIKVLERLKARYGELYTEKNVAISGIHTHAGPGGYLQYVTYIVTSLGF 138

  Fly   138 VPQTFEVMAQGLYLCIKRATDNLVDGRILLSKTTVLNVNINRSPSSYLRNPAEERAQYEHDTDKT 202
            |.|:|:|:..|:...|.:|.::|..|...::|..:|:..:||||||||.|||.||::|::|.||.
plant   139 VRQSFDVVVNGIEQSIVQAHESLRPGSAFVNKGDLLDAGVNRSPSSYLNNPAAERSKYKYDVDKE 203

  Fly   203 LTQLRFVDLENNLLGAFNWYAVHATSMNNTNRLVTSDNVGYAALLLE------------------ 249
            :|.::|||.:....|:|||:|.|.|||:.||.|::.||.|.||..:|
plant   204 MTLVKFVDSQLGPTGSFNWFATHGTSMSRTNSLISGDNKGAAARFMEDWFENGQKNSVSSRNIPR 268

  Fly   250 ------KEYNPNK-------MP------------------------------------------- 258
                  .:::.|:       :|
plant   269 RVSTIVSDFSRNRESYPFLELPNVAILYIAVAERLMWKVMVLFYFVSESRLLDIAATYKSSRGHS 333

  Fly   259 --------------GKGKFVGAFCSSNLGDVSPNIMGPKCSISGNECDLLTSRCPTGEGD-CFAS 308
                          .|.|||.|||.||.||||||.:|..|..:|..||...|.| .|:.: |:..
plant   334 VDKSLDVKTRVRNGSKRKFVSAFCQSNCGDVSPNTLGTFCIDTGLPCDFNHSTC-NGQNELCYGR 397

  Fly   309 GPG-KDMFESTQILGQRLADAALGLLNEQSQESTAREVTGDVRFIHQFVDMPNYN--------GS 364
            ||| .|.||||:|:|::....|:.|.|:.::     ::.|.:.:.|.::|..|.:        ||
plant   398 GPGYPDEFESTRIIGEKQFKMAVELFNKATE-----KLQGKIGYQHAYLDFSNLDVTVPKAGGGS 457

  Fly   365 TYNPLSRKVDKIRGCQPAMGYSFAAGTTDGPGAFSFEQGTTTDNPMWNFVRDFIAAPTQEDIKCH 429
                     :.::.|..|||:.||||||||||||.|:||....|..|..||:.:..|..|.::|.
plant   458 ---------ETVKTCPAAMGFGFAAGTTDGPGAFDFKQGDDQGNVFWRLVRNVLRTPGPEQVQCQ 513

  Fly   430 EPKPILLATGRATFPYEWQPKIVSDQLLKIGDVIIAAVPCEFTTMAGRRLRNQIRAAASAVG--- 491
            :||||||.||....||:|.|.|:..|:|:||.::|.:||.|||||||||||:.|::...:..
plant   514 KPKPILLDTGEMKEPYDWAPSILPIQILRIGQLVILSVPGEFTTMAGRRLRDAIKSFLISSDPKE 578

  Fly   492 -GIDTEVIIAGLTNIYTSYTVTPEEYQAQRYEAASTIFGPHTHSIYMDVFERLTKAMMRNETVDA 555
             ..:..|:||||||.|:.|..|.|||:.||||.|||::|.||.:.|:..|::|..|::...|:..
plant   579 FSNNMHVVIAGLTNTYSQYIATFEEYEVQRYEGASTLYGRHTLTAYIQEFKKLATALVNGLTLPR 643

  Fly   556 GPSPPYMNDVMLSLNTGVLFDGHPINTDFGYVKSQ--PNKEYGINETVKVTYISGNPRNNLFTEK 618
            ||.||.:.|..:||.:.|:.|..|:...||.||:.  |...:...:.|..|:.||.|||:|.||.
plant   644 GPQPPDLLDKQISLLSPVVVDSTPLGVKFGDVKADVPPKSTFRRGQQVNATFWSGCPRNDLMTEG 708

  Fly   619 TYFTIERKINEDRWKVAYTDASWETKMVWHRTNTILGFSEMDIYWDISPQTLPGEYRIRHSGEYK 683
            ::..:|......:|...|.|..:..|..|.|...:...|:..|.|.:....:.|.|||||.|..|
plant   709 SFAVVETLREGGKWAPVYDDDDFSLKFKWSRPAKLSSESQATIEWRVPESAVAGVYRIRHYGASK 773

  Fly   684 YILGGKYPYEGLTHSFTV 701
            .:.|....:.|.:.:|.|
plant   774 SLFGSISSFSGSSSAFVV 791

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CDase	NP_001263109.1	PTZ00487	24..701	CDD:240437	286/780 (37%)
		Ceramidase_alk	25..538	CDD:282576	236/614 (38%)
		Ceramidse_alk_C	540..701	CDD:293653	50/162 (31%)
AT2G38010	NP_973628.1	PTZ00487	26..773	CDD:240437	282/761 (37%)
		Ceramidase_alk	26..626	CDD:282576	236/614 (38%)
		Ceramidse_alk_C	628..775	CDD:293653	47/146 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	423	1.000	Domainoid score	I118
eggNOG	1	0.900	-	-		E1_KOG2232
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10310
Inparanoid	1	1.050	514	1.000	Inparanoid score	I298
OMA	1	1.010	-	-		QHG63482
OrthoDB	1	1.010	-	-		D967085at2759
OrthoFinder	1	1.000	-	-		FOG0003346
OrthoInspector	1	1.000	-	-		otm3163
orthoMCL	1	0.900	-	-		OOG6_103367
Panther	1	1.100	-	-	O	PTHR12670
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3230
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840