DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2224 and RRI1

DIOPT Version :9

Sequence 1:	NP_001263108.1	Gene:	CG2224 / 43617	FlyBaseID:	FBgn0039773	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_010065.2	Gene:	RRI1 / 851310	SGDID:	S000002375	Length:	440	Species:	Saccharomyces cerevisiae

Alignment Length:	177	Identity:	45/177 - (25%)
Similarity:	70/177 - (39%)	Gaps:	32/177 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 SEAAADKTTNSKPSFDRNQKPSYN--RTDSLLAGSLR---LVYVPGDTMEVFLKLA------LAN 267
            :|:.|..:...|||    |:|.::  ...|||...|:   ...:|..|..:..||:      .|.
Yeast    26 TESIALSSMRFKPS----QEPEFHALSQSSLLKTKLKQQSSTDIPSYTHVLISKLSCEKITHYAV 86

  Fly   268 TSKNIETCGVLAGHLSQNQLYITHIITPQQQGTPDSCNTMHEEQIFDVQ--DQM----------- 319
            ...|||..|:|.|...::.:.:.........||....|...|...:.||  |:|
Yeast    87 RGGNIEIMGILMGFTLKDNIVVMDCFNLPVVGTETRVNAQLESYEYMVQYIDEMYNHNDGGDGRD 151

  Fly   320 ----QLITLGWIHTHPTQTAFLSSVDLHTHCSYQIMMPEALAIVCAP 362
                :|..:||.|:||....:||::|:.|....|......:|||..|
Yeast   152 YKGAKLNVVGWFHSHPGYDCWLSNIDIQTQDLNQRFQDPYVAIVVDP 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2224	NP_001263108.1	USP8_dimer	16..119	CDD:286108
CG2224	NP_001263108.1	MPN_AMSH_like	247..419	CDD:163697	35/142 (25%)
RRI1	NP_010065.2	MPN_RPN11_CSN5	62..346	CDD:163700	34/137 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810