DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2224 and AMSH1

DIOPT Version :9

Sequence 1:NP_001263108.1 Gene:CG2224 / 43617 FlyBaseID:FBgn0039773 Length:420 Species:Drosophila melanogaster
Sequence 2:NP_564533.1 Gene:AMSH1 / 841301 AraportID:AT1G48790 Length:507 Species:Arabidopsis thaliana


Alignment Length:529 Identity:149/529 - (28%)
Similarity:219/529 - (41%) Gaps:176/529 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 IEVDKNMPVTRYYRSGTEMLRMANVYLREGNHENAFILYLRYMTLFIEKIRQHPDY-GSVKAEVR 92
            |.||..:.:..|:|....:|:.||::..|.|..:.:::.||:.:|.:|.|..|.|| .|:|:...
plant    17 IGVDNRISLKFYFRIADNILKQANIFRAEKNVIDLYVMLLRFSSLALETIPSHRDYRTSLKSNKE 81

  Fly    93 DINRKIKDEIMPTTEKLR-----------AKLLTHYQ--------------------REY----- 121
            .:..::.| ::...|||:           .||...|.                    ..|     
plant    82 YLRMRLLD-VLTELEKLKPVVQQRIDELYPKLKPRYNVQAHPANGSLGWSSAVKPSFNSYDHAKV 145

  Fly   122 ---------------EQFLASKEAERVKELERERE-----RERERQRQKEREKAGSSAIPSLIPA 166
                           :|||.:...|     ||.|:     |..|....|                
plant   146 RNPPGHNSGYMGSRGQQFLNAAPLE-----ERFRKMSVNFRPNEETLSK---------------- 189

  Fly   167 NLHVLIDEGN-----QPSAPDLGLLDQVVYPN--DFPTGANRSLPGSGLLLPAASEAAADK--TT 222
              |.::..|.     ||...|    .:|.||:  ||          |.:::|:..:....|  .|
plant   190 --HSILGPGGLSAQWQPPKYD----TKVQYPSNIDF----------SPVVIPSFQQLVDSKPMIT 238

  Fly   223 NS----------KPSFDRNQKPSYNRTD------------------------------------- 240
            |.          :||...|:|...|.|:                                     
plant   239 NGSNDEPEKPIVEPSVASNEKIQKNYTEELSSMISFEEPESVNENNLIRQPSPPPVLAEVQDLVP 303

  Fly   241 ---------------SLLAGSLRL-----VYVPGDTMEVFLKLALANTSKNIETCGVLAGHLSQN 285
                           ||...|||.     :::....|:.|::||.:||.||:||||:|||.|...
plant   304 ALCPEVREPECMIENSLPDESLRSESPLELHIATSMMDTFMRLAKSNTKKNLETCGILAGSLKNR 368

  Fly   286 QLYITHIITPQQQGTPDSCNTMHEEQIFDVQDQMQLITLGWIHTHPTQTAFLSSVDLHTHCSYQI 350
            :.|||.:|.|:|:.|.|||...:||:||:|||:..|..||||||||||:.|:||:|:|||.||||
plant   369 KFYITALIIPKQESTSDSCQATNEEEIFEVQDKQSLFPLGWIHTHPTQSCFMSSIDVHTHYSYQI 433

  Fly   351 MMPEALAIVCAPKYNTT--GFFILTPHYGLDYIAQCRQSGFHPH--PND-PPLFMEAQHIRMDNQ 410
            |:|||:|||.||:.::.  |.|.||...|:..|..|.:.|||.|  |.| .|::...:.:.|:..
plant   434 MLPEAVAIVMAPQDSSRNHGIFRLTTPGGMTVIRNCDRRGFHAHSSPEDGGPIYNTCKEVYMNPN 498

  Fly   411 AKIKVIDLR 419
            .|..|||||
plant   499 LKFDVIDLR 507

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2224NP_001263108.1 USP8_dimer 16..119 CDD:286108 27/121 (22%)
MPN_AMSH_like 247..419 CDD:163697 85/181 (47%)
AMSH1NP_564533.1 USP8_dimer 1..104 CDD:401063 24/87 (28%)
MPN_AMSH_like 333..507 CDD:163697 83/173 (48%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 1 1.000 140 1.000 Domainoid score I1534
eggNOG 1 0.900 - - E1_COG1310
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 238 1.000 Inparanoid score I1095
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D411229at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm2605
orthoMCL 1 0.900 - - OOG6_103166
Panther 1 1.100 - - O PTHR12947
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X1584
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
1110.830

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