Protein Alignment CG2224 and AMSH1

DIOPT Version :10

• Sequence 1: NP_651796.1
• Gene: CG2224 / 43617
• FlyBaseID: FBgn0039773
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_564533.1
• Gene: AMSH1 / 841301
• AraportID: AT1G48790
• Length: 507
• Species: Arabidopsis thaliana
• Alignment Length: 529
• Identity: 149/529 - (28%)
• Similarity: 219/529 - (41%)
• Gaps: 176/529 - (33%)

  Fly    29 IEVDKNMPVTRYYRSGTEMLRMANVYLREGNHENAFILYLRYMTLFIEKIRQHPDY-GSVKAEVR 92
            |.||..:.:..|:|....:|:.||::..|.|..:.:::.||:.:|.:|.|..|.|| .|:|:...
plant    17 IGVDNRISLKFYFRIADNILKQANIFRAEKNVIDLYVMLLRFSSLALETIPSHRDYRTSLKSNKE 81

  Fly    93 DINRKIKDEIMPTTEKLR-----------AKLLTHYQ--------------------REY----- 121
            .:..::.| ::...|||:           .||...|.                    ..|
plant    82 YLRMRLLD-VLTELEKLKPVVQQRIDELYPKLKPRYNVQAHPANGSLGWSSAVKPSFNSYDHAKV 145

  Fly   122 ---------------EQFLASKEAERVKELERERE-----RERERQRQKEREKAGSSAIPSLIPA 166
                           :|||.:...|     ||.|:     |..|....|
plant   146 RNPPGHNSGYMGSRGQQFLNAAPLE-----ERFRKMSVNFRPNEETLSK---------------- 189

  Fly   167 NLHVLIDEGN-----QPSAPDLGLLDQVVYPN--DFPTGANRSLPGSGLLLPAASEAAADK--TT 222
              |.::..|.     ||...|    .:|.||:  ||          |.:::|:..:....|  .|
plant   190 --HSILGPGGLSAQWQPPKYD----TKVQYPSNIDF----------SPVVIPSFQQLVDSKPMIT 238

  Fly   223 NS----------KPSFDRNQKPSYNRTD------------------------------------- 240
            |.          :||...|:|...|.|:
plant   239 NGSNDEPEKPIVEPSVASNEKIQKNYTEELSSMISFEEPESVNENNLIRQPSPPPVLAEVQDLVP 303

  Fly   241 ---------------SLLAGSLRL-----VYVPGDTMEVFLKLALANTSKNIETCGVLAGHLSQN 285
                           ||...|||.     :::....|:.|::||.:||.||:||||:|||.|...
plant   304 ALCPEVREPECMIENSLPDESLRSESPLELHIATSMMDTFMRLAKSNTKKNLETCGILAGSLKNR 368

  Fly   286 QLYITHIITPQQQGTPDSCNTMHEEQIFDVQDQMQLITLGWIHTHPTQTAFLSSVDLHTHCSYQI 350
            :.|||.:|.|:|:.|.|||...:||:||:|||:..|..||||||||||:.|:||:|:|||.||||
plant   369 KFYITALIIPKQESTSDSCQATNEEEIFEVQDKQSLFPLGWIHTHPTQSCFMSSIDVHTHYSYQI 433

  Fly   351 MMPEALAIVCAPKYNTT--GFFILTPHYGLDYIAQCRQSGFHPH--PND-PPLFMEAQHIRMDNQ 410
            |:|||:|||.||:.::.  |.|.||...|:..|..|.:.|||.|  |.| .|::...:.:.|:..
plant   434 MLPEAVAIVMAPQDSSRNHGIFRLTTPGGMTVIRNCDRRGFHAHSSPEDGGPIYNTCKEVYMNPN 498

  Fly   411 AKIKVIDLR 419
            .|..|||||
plant   499 LKFDVIDLR 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2224	NP_651796.1	USP8_dimer	11..120	CDD:462647	27/122 (22%)
		MPN_AMSH_like	247..419	CDD:163697	85/181 (47%)
AMSH1	NP_564533.1	USP8_dimer	1..104	CDD:462647	24/87 (28%)
		MPN_AMSH_like	333..507	CDD:163697	83/173 (48%)