DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2224 and Mpnd

DIOPT Version :9

Sequence 1:	NP_001263108.1	Gene:	CG2224 / 43617	FlyBaseID:	FBgn0039773	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	XP_038940132.1	Gene:	Mpnd / 681944	RGDID:	1589335	Length:	488	Species:	Rattus norvegicus

Alignment Length:	228	Identity:	52/228 - (22%)
Similarity:	76/228 - (33%)	Gaps:	74/228 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   204 PGSGLLLPAASEAAADKTTNSKPSFDRNQKPSYNRTDSL-------LAGSLRLVYVPGDTMEVFL 261
            ||.|.|.|.|:                   |...|.|.:       :.||......|...:|| .
  Rat   201 PGKGSLEPEAT-------------------PPGKRVDKVRVPVRYCMLGSRDSARNPHTLVEV-T 245

  Fly   262 KLALAN--------TSKNI-------------ETCGVLAGHLSQNQLYITHIIT---PQQQGTPD 302
            ..|..|        .|.|:             |..|.|.|....|...:|.:..   ..:.|.||
  Rat   246 SFAAINKFQPFNVAVSSNVLFLLDFHCHLTRSEVVGYLGGRWDINNQMLTVLRAFPCRSRLGDPD 310

  Fly   303 SCNTMHEEQIFDVQDQMQLITLGWIHTHPTQTAFLSSVDLHTHCSYQIMM-------PEALAIVC 360
            :..|: ||:|..|.....|..:||.|:||...|..|..|:.....||:.:       ...||::|
  Rat   311 TAATV-EEEIHQVLFLRGLSLVGWYHSHPHSPAAPSLQDIDAQMEYQLRLQGSNNGFQPCLALLC 374

  Fly   361 APKYN--------TTGFFILTP-------HYGL 378
            :|.|:        ...|:::.|       .||:
  Rat   375 SPYYSGNPGPESKICPFWVMPPPEQQRPSDYGI 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2224	NP_001263108.1	USP8_dimer	16..119	CDD:286108
CG2224	NP_001263108.1	MPN_AMSH_like	247..419	CDD:163697	41/178 (23%)
Mpnd	XP_038940132.1	RAMA	57..157	CDD:408526
Mpnd	XP_038940132.1	MPN_2A_DUB	252..437	CDD:163698	36/157 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900