Protein Alignment CG2224 and Mpnd

DIOPT Version :9

• Sequence 1: NP_001263108.1
• Gene: CG2224 / 43617
• FlyBaseID: FBgn0039773
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_080806.4
• Gene: Mpnd / 68047
• MGIID: 1915297
• Length: 487
• Species: Mus musculus
• Alignment Length: 327
• Identity: 67/327 - (20%)
• Similarity: 106/327 - (32%)
• Gaps: 115/327 - (35%)

  Fly   108 KLRAKLLTHYQ----REYEQFLASKEAERVKELERERERERERQRQKEREKAGSSAIPSLIPANL 168
            |.:.:.|..|:    |.::..:....|:.....|.| |.|...:.::|...||.|:
Mouse   139 KYKGQKLDKYKAAWLRRHQLHMPVATADESPTSEGE-EEELLLEEEEEDVLAGVSS--------- 193

  Fly   169 HVLIDEGNQPSAPDLGLLDQVVYPNDFPTGANRSLPGSGLLLPAASEAAADKTTNSKPSFDRNQK 233
               .|:|::|                         ||.|.|.|.|:
Mouse   194 ---EDKGHRP-------------------------PGKGSLEPEAT------------------- 211

  Fly   234 PSYNRTDSL-------LAGSLRLVYVPGDTMEVFLKLALAN--------TSKNI----------- 272
            |...|.|.:       :.||......|...:|| ...|..|        .|.|:
Mouse   212 PPGKRMDKVPVPIRYCMLGSRDSARNPHTLVEV-TSFAAINKFQPFNVAVSSNVLFLLDFHCHLT 275

  Fly   273 --ETCGVLAGHLSQNQLYITHIIT---PQQQGTPDSCNTMHEEQIFDVQDQMQLITLGWIHTHPT 332
              |..|.|.|....|...:|.:..   ..:.|..|:..|: ||:|:.|.....|..:||.|:||.
Mouse   276 RSEVVGYLGGRWDINNQMLTVLRAFPCRSRLGDTDTAATV-EEEIYQVLFLRGLSLVGWYHSHPH 339

  Fly   333 QTAFLSSVDLHTHCSYQIMM-------PEALAIVCAPKYN--------TTGFFILTP------HY 376
            ..|..|..|:.....||:.:       ...||::|:|.|:        ...|:::.|      .|
Mouse   340 SPAVPSLQDIDAQMEYQLRLQGSSNGFQPCLALLCSPYYSGNPGPESKICPFWVMPPPEQRPSDY 404

  Fly   377 GL 378
            |:
Mouse   405 GI 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2224	NP_001263108.1	USP8_dimer	16..119	CDD:286108	3/14 (21%)
		MPN_AMSH_like	247..419	CDD:163697	40/177 (23%)
Mpnd	NP_080806.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	163..217		19/110 (17%)
		MPN_2A_DUB	252..436	CDD:163698	35/156 (22%)
		JAMM motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01182	335..348		5/12 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900