DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2224 and mysm1

DIOPT Version :9

Sequence 1:	NP_001263108.1	Gene:	CG2224 / 43617	FlyBaseID:	FBgn0039773	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	XP_021324132.1	Gene:	mysm1 / 561225	ZFINID:	ZDB-GENE-041014-28	Length:	828	Species:	Danio rerio

Alignment Length:	380	Identity:	84/380 - (22%)
Similarity:	130/380 - (34%)	Gaps:	134/380 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 EYEQFLASK--EAERV-KELERERERERERQRQKEREKAGSSAIPSLIPANLHVLIDEGNQ---- 177
            |.|..||.|  .||.: :|:|.:.|.|.|..|..|:|          :..:|:.:.:|..|
Zfish   289 EEETELADKCESAECLEEEVEDQEEDEEEELRAPEQE----------VELDLNTITEEEKQAISE 343

  Fly   178 -----PS-APDLGL------LDQVVYPNDFPTGANRSLPGSGLL----------------LPAAS 214
                 || .|:..|      |||  :....|...|::....||.                |..|.
Zfish   344 FFEGRPSKTPERYLKIRNYILDQ--WRRSKPKYLNKTSVRPGLKNCGDVNCIGRIHTYLELIGAI 406

  Fly   215 EAAADKTTNSKPSF-DRNQ----KPSY------NRTDSLLAGSLRLVYVPGDTMEVFLKLALANT 268
            ....|:...::|.. ||::    |.|.      .|..|:.....|:..|.|:..:
Zfish   407 NFNCDQAIYNRPRLVDRSRLKESKDSLEAYHLAQRLQSMRTRKRRIRDVWGNWCD---------- 461

  Fly   269 SKNIETCGVLAGHLSQNQLYITH----------IITPQQQGTPD-----SCNTMHEEQIFDVQDQ 318
            :|::|  |....|||..:|.|..          ...|:|:|:.|     .|.|..||:    |:.
Zfish   462 AKDLE--GQTYEHLSAEELAIRREEMKKKGPRPSKLPKQRGSFDPFQLIPCKTFGEER----QEP 520

  Fly   319 MQLITLGWIHTHPTQTAFLSSVDLHTHCSYQIMM----------PEALAIVCAPKYN--TTGFFI 371
            ..:|..         ...|..:|:|.|.|...::          .:.|.|..|...|  :||.
Zfish   521 YSVIVC---------AEALIVMDIHAHVSMGEVIGLLGGTYEEEDKVLKICSAEPCNSLSTGL-- 574

  Fly   372 LTPHYGLDYIAQCRQS------------GFHPHPN-DP-PLFMEAQHIRMDNQAK 412
               ...:|.::|.:.|            .:|.||. || |...:     :|.|||
Zfish   575 ---QCEMDPVSQTQASEVLGVKGLSVVGWYHSHPAFDPNPSLRD-----IDTQAK 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2224	NP_001263108.1	USP8_dimer	16..119	CDD:286108
CG2224	NP_001263108.1	MPN_AMSH_like	247..419	CDD:163697	45/207 (22%)
mysm1	XP_021324132.1	SANT	107..150	CDD:238096
		SWIRM	331..408	CDD:309539	15/78 (19%)
		MPN_2A_DUB	517..699	CDD:163698	26/128 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900