DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2224 and eif3f

DIOPT Version :9

Sequence 1:	NP_001263108.1	Gene:	CG2224 / 43617	FlyBaseID:	FBgn0039773	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_001186938.1	Gene:	eif3f / 557270	ZFINID:	ZDB-GENE-100215-2	Length:	273	Species:	Danio rerio

Alignment Length:	145	Identity:	28/145 - (19%)
Similarity:	54/145 - (37%)	Gaps:	37/145 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   276 GVLAGHLSQNQLYITHIITPQQQGTPDS-------CNTMHE--------EQI-------FDVQDQ 318
            |.|.|...::.:.:|:..:.....:.|.       ...|:|        |.|       ||:.:.
Zfish    34 GTLLGTADKHSVDVTNCFSVPHNESEDEVAVDMEFAKNMYELHKKVSPSEVIVGWYATGFDITEH 98

  Fly   319 MQLITLGWIHTHP------TQTAFLSS-VDLHTHCSYQIMMP-EALAIVCAP---KYNTTGFFIL 372
            ..||...:....|      ..||..|: :::..:.|.|:.:| :.:.::..|   ||    .:..
Zfish    99 SVLIHEYYSREAPNPIHLTVDTALQSNKMNIRAYVSSQMGVPGKTVGVMFTPLSVKY----IYYD 159

  Fly   373 TPHYGLDYIAQCRQS 387
            |...|:|.:.:.|.|
Zfish   160 TERIGVDLLQRTRAS 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2224	NP_001263108.1	USP8_dimer	16..119	CDD:286108
CG2224	NP_001263108.1	MPN_AMSH_like	247..419	CDD:163697	28/145 (19%)
eif3f	NP_001186938.1	MPN_eIF3f	8..270	CDD:163695	28/145 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900