Protein Alignment CG2224 and Psmd7

DIOPT Version :10

• Sequence 1: NP_651796.1
• Gene: CG2224 / 43617
• FlyBaseID: FBgn0039773
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_001100896.1
• Gene: Psmd7 / 307821
• RGDID: 1306902
• Length: 320
• Species: Rattus norvegicus
• Alignment Length: 910
• Identity: 182/910 - (20%)
• Similarity: 272/910 - (29%)
• Gaps: 349/910 - (38%)

  Fly    13 QQQRSGGNGPQEEQQQRTVGRGFAVAAEQPQEHQQRPALAAGD-----------DEEHQGEARLL 66
            |||.|      ::.::||:.|..|.....||..:..| |::|.           |::..     |
  Rat  1005 QQQTS------DKHKKRTMPRKLAPLRPAPQLPRLLP-LSSGSIGNISNPGIIIDQQIS-----L 1057

  Fly    67 AAPH-----------------AHRSRPAVAE-------REKEEREGDDGRRPAAAVATPTASRRR 107
            ..||                 .||:.|:::.       .:.:..|......|.........|:..
  Rat  1058 NVPHNLQSDNVIVIKAHENVNTHRTVPSLSPDLVVQLVPQTQVAENTTSSLPRKTTPRSDVSQTA 1122

  Fly   108 SRAVLVPAAGGSGDRSGEGGSEEGAGSSGSVGGSKRRSTRASAAQRHSSVVTAAAAPVDSGEAVL 172
            .....|.::|.:|.|:                              ..|..|||.|.|||.:.||
  Rat  1123 KDIPSVQSSGENGQRT------------------------------VFSPQTAAPAAVDSSQFVL 1157

  Fly   173 RQ-------------PDDTGTVSRPARSSSSAP-------------STSSTSGGAA--------- 202
            .|             |.|:..:::||...|...             ||:||:...:
  Rat  1158 VQTVSPTGPPQFLLLPQDSLVLNQPASLPSEGTLQNLSQQTSHLDISTTSTALKNSEKTEVHLNN 1222

  Fly   203 PTSLL---------RQHGSGGTSG-------GHSLHQQPNRSARALGTATDSNKD---------- 241
            ||:.|         ||.......|       ..:|...|..:......:.||:.|
  Rat  1223 PTTSLPVSREEDGERQEVDEEMVGDRWEEEMASALFGSPLLALSESSCSPDSSPDASMDSGSDAM 1287

  Fly   242 -----------SVHRAAGGDDDDD-DEEEDGEEPATEQHGAVVEEAGNRYSIAVSSEQQQQQRSD 294
                       |||.|:...:..| .:...|:|...:..|...:.:||....|..||.::.:..|
  Rat  1288 VRVEMEDGELPSVHSASATQETPDVHKHSSGDEKEQQSSGGEKQNSGNEEGRAEESESRKDEAQD 1352

  Fly   295 DD----DNNDCSPRSKRRRKMLNDNVGSGGGGGNR---NGAAPGGGTPASTASPMDASNCDQNGH 352
            :|    .|.|.....||      |..|||..|...   :|...|.|.........|....|::..
  Rat  1353 EDKGGEKNEDGEGDGKR------DEGGSGDKGREEKDGDGEKDGDGERDEEEEDFDDLTQDEDEE 1411

  Fly   353 TVANSSSSSS----------------------------SNSNNATVS-------NSNNNPA---- 378
            .|.:|:|..|                            |..:|:..|       ||.|:||
  Rat  1412 EVMSSASEESVLSVPELQETMEKLTWLASERRLCREGDSEEDNSPTSPTSPTSPNSQNSPASQNS 1476

  Fly   379 -------ENDNGM-------GNSSNGLTTNGEAGGG----------GGGGSGSGGSSRPSPAHRT 419
                   |:|..|       |.........|:|..|          ||.|.|.|   ||.|  |:
  Rat  1477 QEENSEDEDDGAMKGDELEAGEGEGEKLPEGDAPAGDDPPQISEKVGGRGRGRG---RPPP--RS 1536

  Fly   420 VK----LDRTNQDIVRLI---GQHL---------KDIG-----LERSAEMLMQEAGCCLEHPAAS 463
            :|    .:|.::|..:|:   ..|:         ||:.     |.|..|.|....|      ...
  Rat  1537 LKRGRRQERGSKDASKLLLLYDDHILDNDPMRESKDMAYAQAYLNRVREALQDVPG------KVE 1595

  Fly   464 KFRIHVLSGDWNKADHDLQEL-----QSLVD---IRSDRASLNEMKFLLLEQKYLEYLEEGRPID 520
            :|...:...|.....|.:.||     |.|.|   :..|.|:     |||.||.    ||.|
  Rat  1596 EFLGLLYEFDQAGESHSVIELFAQLKQLLKDWPELLKDFAA-----FLLPEQA----LECG---- 1647

  Fly   521 ALHVLRNELTPLQHKTPRVHQLS-SYMMCTNNAELYARAGWEGKGPKSRTRLMDRLQSYLPATVM 584
                |..|....:.....:.||. |:                |:.|....:::..|||..|
  Rat  1648 ----LFEEQQAFERSRRFLRQLEISF----------------GENPSHYQKIVRALQSGSP---- 1688

  Fly   585 LPPRRLRSLLVQAVELQNDRCQCHDMTWSTSIDSVSLLVDHNCSADGFPLQPLQVLNDHSDEVWF 649
            |.|..:..|..|...|...........|        :..|.....   |.:|.|    ..:.||
  Rat  1689 LSPAGIEELKTQMATLLKGHTHLQGEFW--------MFFDEMRPP---PARPGQ----FEEAVW- 1737

  Fly   650 CKFSPDGRRLATGSKDNSVI-------VW---------EVDP-------VKLLLRNKRSFEGHTY 691
                |:.  :|||:...:.:       ||         ::|.       .::..|:||..|.|||
  Rat  1738 ----PED--VATGTDGEAGVSVTSRGGVWGGFEEVTLPDLDEDEESHKIRQISSRSKRRKELHTY 1796

  Fly   692  691
              Rat  1797  1796

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2224	NP_651796.1	USP8_dimer	11..120	CDD:462647	25/141 (18%)
		MPN_AMSH_like	247..419	CDD:163697	52/242 (21%)
Psmd7	NP_001100896.1	MPN_RPN7_8	7..285	CDD:163693