DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2224 and Cops6

DIOPT Version :9

Sequence 1:	NP_001263108.1	Gene:	CG2224 / 43617	FlyBaseID:	FBgn0039773	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_001100599.1	Gene:	Cops6 / 304343	RGDID:	1309919	Length:	344	Species:	Rattus norvegicus

Alignment Length:	269	Identity:	51/269 - (18%)
Similarity:	91/269 - (33%)	Gaps:	77/269 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   203 LPGSGLLLPAASEAAADKTTNSKPSFDRNQKPSYNRTDSLLA----GSLRLVYVP---------- 253
            |.|:|.:..||:.|||.....:..|...:.........|::|    ||:.:...|
  Rat     8 LAGAGKMAAAAAAAAAAAAAAANGSGGSSGMEVDAAVPSVMASGVTGSVSVALHPLVILNISDHW 72

  Fly   254 -------GDTMEVFLKLALANTSKNIETCG--VLAGHLSQNQLYI--THIITPQQQ--------- 298
                   |..|:|...|......:|||...  .|..|..:.::.|  .:..|.::|
  Rat    73 IRMRSQEGRPMQVIGALIGKQEGRNIEVMNSFELLSHTVEKKIIIDKEYYYTKEEQFKQVFKELE 137

  Fly   299 --------GTPDSCNTMHEEQIFDVQDQMQLITLGWI--HTHPTQTAFLSSVD--------LHTH 345
                    |.||..:....:|:.::.:....:.|..:  ||....:.|.|.:|        |...
  Rat   138 FLGWYTTGGPPDPSDIHVHKQVCEIIESPLFLKLNPMTKHTDLPVSVFESVIDIINGEATMLFAE 202

  Fly   346 CSYQIMMPEALAIVCAPKYNTTGFFILTPHYGLDYIAQCRQSGFHPHPNDPPLFMEAQHIRMDNQ 410
            .:|.:...||..|                  |:|::|:...:|...:..      .|:|:...:.
  Rat   203 LTYTLATEEAERI------------------GVDHVARMTATGSGENST------VAEHLIAQHS 243

  Fly   411 AKIKVIDLR 419
            | ||::..|
  Rat   244 A-IKMLHSR 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2224	NP_001263108.1	USP8_dimer	16..119	CDD:286108
CG2224	NP_001263108.1	MPN_AMSH_like	247..419	CDD:163697	37/219 (17%)
Cops6	NP_001100599.1	MPN_CSN6	56..338	CDD:163694	38/221 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900