DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2224 and Cops6

DIOPT Version :9

Sequence 1:	NP_001263108.1	Gene:	CG2224 / 43617	FlyBaseID:	FBgn0039773	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_036132.1	Gene:	Cops6 / 26893	MGIID:	1349439	Length:	324	Species:	Mus musculus

Alignment Length:	253	Identity:	49/253 - (19%)
Similarity:	87/253 - (34%)	Gaps:	60/253 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   198 GANRSLPGSGLLLPAASEAAADKTTNSKPSFDRNQKPSYNRTDSLLAGSLRLVYVPGDTMEVFLK 262
            |||.|...||:.:.||..:..........|...:.....|.:|..    :|:....|..|:|...
Mouse     8 GANGSGGSSGMEVDAAVPSVMASGVTGSVSVALHPLVILNISDHW----IRMRSQEGRPMQVIGA 68

  Fly   263 LALANTSKNIETCG--VLAGHLSQNQLYI--THIITPQQQ-----------------GTPDSCNT 306
            |......:|||...  .|..|..:.::.|  .:..|.::|                 |.||..:.
Mouse    69 LIGKQEGRNIEVMNSFELLSHTVEEKIIIDKEYYYTKEEQFKQVFKELEFLGWYTTGGPPDPSDI 133

  Fly   307 MHEEQIFDVQDQMQLITLGWI--HTHPTQTAFLSSVD--------LHTHCSYQIMMPEALAIVCA 361
            ...:|:.::.:....:.|..:  ||....:.|.|.:|        |....:|.:...||..|
Mouse   134 HVHKQVCEIIESPLFLKLNPMTKHTDLPVSVFESVIDIINGEATMLFAELTYTLATEEAERI--- 195

  Fly   362 PKYNTTGFFILTPHYGLDYIAQCRQSGFHPHPNDPPLFMEAQHIRMDNQAKIKVIDLR 419
                           |:|::|:...:|...:..      .|:|:...:.| ||::..|
Mouse   196 ---------------GVDHVARMTATGSGENST------VAEHLIAQHSA-IKMLHSR 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2224	NP_001263108.1	USP8_dimer	16..119	CDD:286108
CG2224	NP_001263108.1	MPN_AMSH_like	247..419	CDD:163697	37/202 (18%)
Cops6	NP_036132.1	MPN_CSN6	36..318	CDD:163694	41/225 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900